Metastasis to the male breast from carcinoma of the urinary bladder: a rare case report
Metastasis to the male breast is rarer than that of the female breast. Primary tumors of the urinary bladder to metastasize to the breast is more uncommon than other sites like lungs, ovary, or stomach. We report a case of a 59-year-old male patient with proven high-grade urothelial carcinoma of the...
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| Format: | Article |
| Language: | English |
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Association of Clinical Pathologists of Nepal
2021-09-01
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| Series: | Journal of Pathology of Nepal |
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| Online Access: | https://www.nepjol.info/index.php/JPN/article/view/31629 |
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| author | Swechha Maskey Kapendra Shekhar Amatya Banita Gurung Suniti Shrestha Moushami Singh Shivani Sharma Hari Prasad Dhakal |
| author_facet | Swechha Maskey Kapendra Shekhar Amatya Banita Gurung Suniti Shrestha Moushami Singh Shivani Sharma Hari Prasad Dhakal |
| author_sort | Swechha Maskey |
| collection | DOAJ |
| description | Metastasis to the male breast is rarer than that of the female breast. Primary tumors of the urinary bladder to metastasize to the breast is more uncommon than other sites like lungs, ovary, or stomach. We report a case of a 59-year-old male patient with proven high-grade urothelial carcinoma of the bladder with lungs and anterior abdominal metastasis, presented with ulceroproliferative mass in the left breast nipple-areolar complex. Wide local excision was done and was sent for histopathological examination which showed neoplastic cells, morphologically resembling urothelial carcinoma. Immunohistochemical staining showed tumor cells positive for CK5/6, p63, GATA3, and Uroplankin, which confirmed the diagnosis and demonstrated the urothelial origin. There are no such cases reported to date in Nepal and very few cases are reported worldwide. Diagnostic accuracy depends on histologic analysis. Distinguishing between metastasis to the breast and primary breast tumor is important for therapy and prognosis. |
| format | Article |
| id | doaj-art-0d91fc3d65de4a8e922542cc0f25e079 |
| institution | Kabale University |
| issn | 2091-0797 2091-0908 |
| language | English |
| publishDate | 2021-09-01 |
| publisher | Association of Clinical Pathologists of Nepal |
| record_format | Article |
| series | Journal of Pathology of Nepal |
| spelling | doaj-art-0d91fc3d65de4a8e922542cc0f25e0792025-08-21T07:13:24ZengAssociation of Clinical Pathologists of NepalJournal of Pathology of Nepal2091-07972091-09082021-09-011121870187210.3126/jpn.v11i1.3162928428Metastasis to the male breast from carcinoma of the urinary bladder: a rare case reportSwechha Maskey0https://orcid.org/0000-0002-4641-4183Kapendra Shekhar Amatya1Banita Gurung2Suniti Shrestha3Moushami Singh4Shivani Sharma5Hari Prasad Dhakal6Nepal cancer hospital and research centerNepal Cancer Hospital and Research CenterNepal Cancer Hospital and Research CenterNepal Cancer Hospital and Research CenterNepal Cancer Hospital and Research CenterCore Diagnostics, Gurgaon, IndiaNepal Cancer Hospital and Research CenterMetastasis to the male breast is rarer than that of the female breast. Primary tumors of the urinary bladder to metastasize to the breast is more uncommon than other sites like lungs, ovary, or stomach. We report a case of a 59-year-old male patient with proven high-grade urothelial carcinoma of the bladder with lungs and anterior abdominal metastasis, presented with ulceroproliferative mass in the left breast nipple-areolar complex. Wide local excision was done and was sent for histopathological examination which showed neoplastic cells, morphologically resembling urothelial carcinoma. Immunohistochemical staining showed tumor cells positive for CK5/6, p63, GATA3, and Uroplankin, which confirmed the diagnosis and demonstrated the urothelial origin. There are no such cases reported to date in Nepal and very few cases are reported worldwide. Diagnostic accuracy depends on histologic analysis. Distinguishing between metastasis to the breast and primary breast tumor is important for therapy and prognosis.https://www.nepjol.info/index.php/JPN/article/view/31629male breast; metastasis; urothelial carcinoma; |
| spellingShingle | Swechha Maskey Kapendra Shekhar Amatya Banita Gurung Suniti Shrestha Moushami Singh Shivani Sharma Hari Prasad Dhakal Metastasis to the male breast from carcinoma of the urinary bladder: a rare case report Journal of Pathology of Nepal male breast; metastasis; urothelial carcinoma; |
| title | Metastasis to the male breast from carcinoma of the urinary bladder: a rare case report |
| title_full | Metastasis to the male breast from carcinoma of the urinary bladder: a rare case report |
| title_fullStr | Metastasis to the male breast from carcinoma of the urinary bladder: a rare case report |
| title_full_unstemmed | Metastasis to the male breast from carcinoma of the urinary bladder: a rare case report |
| title_short | Metastasis to the male breast from carcinoma of the urinary bladder: a rare case report |
| title_sort | metastasis to the male breast from carcinoma of the urinary bladder a rare case report |
| topic | male breast; metastasis; urothelial carcinoma; |
| url | https://www.nepjol.info/index.php/JPN/article/view/31629 |
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