House dust mite allergy – Management

Allergen vulnerability is highly individual specific. House dust mites (HDMs) are major sources of airborne allergens, found not only in houses but also detected in workplaces and most schools. The two most common HDM species from the Pyroglyphidae family, namely Dermatophagoides pteronyssinus and D...

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Main Authors: P. C. Kathuria, Manisha Rai
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Indian Journal of Allergy Asthma and Immunology
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Online Access:https://journals.lww.com/ijaa/fulltext/2024/38020/house_dust_mite_allergy___management.1.aspx
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author P. C. Kathuria
Manisha Rai
author_facet P. C. Kathuria
Manisha Rai
author_sort P. C. Kathuria
collection DOAJ
description Allergen vulnerability is highly individual specific. House dust mites (HDMs) are major sources of airborne allergens, found not only in houses but also detected in workplaces and most schools. The two most common HDM species from the Pyroglyphidae family, namely Dermatophagoides pteronyssinus and Dermatophagoides farinae are responsible for 90% of sensitization and allergic symptoms. Clinical conditions due to HDM allergen are rhinitis, conjunctivitis, asthma and/or atopic dermatitis (AD), and rare severe systemic reaction. Accurate diagnosis by skin prick test, specific immunoglobulin E (extract and component-based), or nasal provocation test with standardized HDM extract in contest with clinically relevant exposure to dust mites is fundamental for successful treatment. Allergen immunotherapy (AIT) is the only treatment providing sustained efficacy for moderate-to-severe allergic rhinitis, allergic asthma, and AD. This review will mainly focus on the description of HDM allergens, immunology, efficacy, and HDM-AIT (subcutaneous immunotherapy and sublingual immunotherapy).
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spelling doaj-art-0d624fdce0b645f7a54f162f653df6d32025-01-16T10:25:25ZengWolters Kluwer Medknow PublicationsIndian Journal of Allergy Asthma and Immunology0972-66912320-47452024-12-01382475810.4103/ijaai.ijaai_27_24House dust mite allergy – ManagementP. C. KathuriaManisha RaiAllergen vulnerability is highly individual specific. House dust mites (HDMs) are major sources of airborne allergens, found not only in houses but also detected in workplaces and most schools. The two most common HDM species from the Pyroglyphidae family, namely Dermatophagoides pteronyssinus and Dermatophagoides farinae are responsible for 90% of sensitization and allergic symptoms. Clinical conditions due to HDM allergen are rhinitis, conjunctivitis, asthma and/or atopic dermatitis (AD), and rare severe systemic reaction. Accurate diagnosis by skin prick test, specific immunoglobulin E (extract and component-based), or nasal provocation test with standardized HDM extract in contest with clinically relevant exposure to dust mites is fundamental for successful treatment. Allergen immunotherapy (AIT) is the only treatment providing sustained efficacy for moderate-to-severe allergic rhinitis, allergic asthma, and AD. This review will mainly focus on the description of HDM allergens, immunology, efficacy, and HDM-AIT (subcutaneous immunotherapy and sublingual immunotherapy).https://journals.lww.com/ijaa/fulltext/2024/38020/house_dust_mite_allergy___management.1.aspxacarus siroblomia tropicalisdermatophagoides farinaedermatophagoides pteronyssinushouse dust mitestorage mitesubcutaneous immunotherapysublingual immunotherapy
spellingShingle P. C. Kathuria
Manisha Rai
House dust mite allergy – Management
Indian Journal of Allergy Asthma and Immunology
acarus siro
blomia tropicalis
dermatophagoides farinae
dermatophagoides pteronyssinus
house dust mite
storage mite
subcutaneous immunotherapy
sublingual immunotherapy
title House dust mite allergy – Management
title_full House dust mite allergy – Management
title_fullStr House dust mite allergy – Management
title_full_unstemmed House dust mite allergy – Management
title_short House dust mite allergy – Management
title_sort house dust mite allergy management
topic acarus siro
blomia tropicalis
dermatophagoides farinae
dermatophagoides pteronyssinus
house dust mite
storage mite
subcutaneous immunotherapy
sublingual immunotherapy
url https://journals.lww.com/ijaa/fulltext/2024/38020/house_dust_mite_allergy___management.1.aspx
work_keys_str_mv AT pckathuria housedustmiteallergymanagement
AT manisharai housedustmiteallergymanagement