House dust mite allergy – Management
Allergen vulnerability is highly individual specific. House dust mites (HDMs) are major sources of airborne allergens, found not only in houses but also detected in workplaces and most schools. The two most common HDM species from the Pyroglyphidae family, namely Dermatophagoides pteronyssinus and D...
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Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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Series: | Indian Journal of Allergy Asthma and Immunology |
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Online Access: | https://journals.lww.com/ijaa/fulltext/2024/38020/house_dust_mite_allergy___management.1.aspx |
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author | P. C. Kathuria Manisha Rai |
author_facet | P. C. Kathuria Manisha Rai |
author_sort | P. C. Kathuria |
collection | DOAJ |
description | Allergen vulnerability is highly individual specific. House dust mites (HDMs) are major sources of airborne allergens, found not only in houses but also detected in workplaces and most schools. The two most common HDM species from the Pyroglyphidae family, namely Dermatophagoides pteronyssinus and Dermatophagoides farinae are responsible for 90% of sensitization and allergic symptoms. Clinical conditions due to HDM allergen are rhinitis, conjunctivitis, asthma and/or atopic dermatitis (AD), and rare severe systemic reaction. Accurate diagnosis by skin prick test, specific immunoglobulin E (extract and component-based), or nasal provocation test with standardized HDM extract in contest with clinically relevant exposure to dust mites is fundamental for successful treatment. Allergen immunotherapy (AIT) is the only treatment providing sustained efficacy for moderate-to-severe allergic rhinitis, allergic asthma, and AD. This review will mainly focus on the description of HDM allergens, immunology, efficacy, and HDM-AIT (subcutaneous immunotherapy and sublingual immunotherapy). |
format | Article |
id | doaj-art-0d624fdce0b645f7a54f162f653df6d3 |
institution | Kabale University |
issn | 0972-6691 2320-4745 |
language | English |
publishDate | 2024-12-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Indian Journal of Allergy Asthma and Immunology |
spelling | doaj-art-0d624fdce0b645f7a54f162f653df6d32025-01-16T10:25:25ZengWolters Kluwer Medknow PublicationsIndian Journal of Allergy Asthma and Immunology0972-66912320-47452024-12-01382475810.4103/ijaai.ijaai_27_24House dust mite allergy – ManagementP. C. KathuriaManisha RaiAllergen vulnerability is highly individual specific. House dust mites (HDMs) are major sources of airborne allergens, found not only in houses but also detected in workplaces and most schools. The two most common HDM species from the Pyroglyphidae family, namely Dermatophagoides pteronyssinus and Dermatophagoides farinae are responsible for 90% of sensitization and allergic symptoms. Clinical conditions due to HDM allergen are rhinitis, conjunctivitis, asthma and/or atopic dermatitis (AD), and rare severe systemic reaction. Accurate diagnosis by skin prick test, specific immunoglobulin E (extract and component-based), or nasal provocation test with standardized HDM extract in contest with clinically relevant exposure to dust mites is fundamental for successful treatment. Allergen immunotherapy (AIT) is the only treatment providing sustained efficacy for moderate-to-severe allergic rhinitis, allergic asthma, and AD. This review will mainly focus on the description of HDM allergens, immunology, efficacy, and HDM-AIT (subcutaneous immunotherapy and sublingual immunotherapy).https://journals.lww.com/ijaa/fulltext/2024/38020/house_dust_mite_allergy___management.1.aspxacarus siroblomia tropicalisdermatophagoides farinaedermatophagoides pteronyssinushouse dust mitestorage mitesubcutaneous immunotherapysublingual immunotherapy |
spellingShingle | P. C. Kathuria Manisha Rai House dust mite allergy – Management Indian Journal of Allergy Asthma and Immunology acarus siro blomia tropicalis dermatophagoides farinae dermatophagoides pteronyssinus house dust mite storage mite subcutaneous immunotherapy sublingual immunotherapy |
title | House dust mite allergy – Management |
title_full | House dust mite allergy – Management |
title_fullStr | House dust mite allergy – Management |
title_full_unstemmed | House dust mite allergy – Management |
title_short | House dust mite allergy – Management |
title_sort | house dust mite allergy management |
topic | acarus siro blomia tropicalis dermatophagoides farinae dermatophagoides pteronyssinus house dust mite storage mite subcutaneous immunotherapy sublingual immunotherapy |
url | https://journals.lww.com/ijaa/fulltext/2024/38020/house_dust_mite_allergy___management.1.aspx |
work_keys_str_mv | AT pckathuria housedustmiteallergymanagement AT manisharai housedustmiteallergymanagement |