Exosome therapy in female reproductive aging

As life expectancy continues to extend, the adverse effects of reproductive aging on female health have become progressively conspicuous. Despite the extant focus on symptom alleviation, a paucity of pharmaceutical interventions addresses the underlying causative factors. Exosome therapy, acknowledg...

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Main Authors: Mengtong Zhang, Sichen Zhang, Shaowei Wang
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Extracellular Vesicle
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2773041724000039
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author Mengtong Zhang
Sichen Zhang
Shaowei Wang
author_facet Mengtong Zhang
Sichen Zhang
Shaowei Wang
author_sort Mengtong Zhang
collection DOAJ
description As life expectancy continues to extend, the adverse effects of reproductive aging on female health have become progressively conspicuous. Despite the extant focus on symptom alleviation, a paucity of pharmaceutical interventions addresses the underlying causative factors. Exosome therapy, acknowledged for its relatively safe cell-free approach, emerges as a promising avenue. Notably, exosomes derived from stem cells exhibit comparable efficacy to their cellular counterparts. Nevertheless, extant methodologies for exosome production exhibit several limitations, particularly in achieving high-caliber, large-scale manufacturing. Consequently, this review is dedicated to elucidating the ongoing research endeavors and advancements of exosome therapy pertaining to the female reproductive aging.
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series Extracellular Vesicle
spelling doaj-art-0d14aba5be804594b34332b59e20d9eb2024-11-23T06:34:54ZengElsevierExtracellular Vesicle2773-04172024-06-013100036Exosome therapy in female reproductive agingMengtong Zhang0Sichen Zhang1Shaowei Wang2Department of Gynecology and Obstetrics, Beijing Hospital, National Center of Gerontology, PR ChinaDepartment of Gynecology and Obstetrics, Beijing Hospital, National Center of Gerontology, PR China; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, PR China; Corresponding author. Department of Gynecology and Obstetrics, Beijing Hospital, National Center of Gerontology, PR China.Department of Gynecology and Obstetrics, Beijing Hospital, National Center of Gerontology, PR China; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, PR China; Corresponding author. epartment of Gynecology and Obstetrics, Beijing Hospital, National Center of Gerontology, PR China.As life expectancy continues to extend, the adverse effects of reproductive aging on female health have become progressively conspicuous. Despite the extant focus on symptom alleviation, a paucity of pharmaceutical interventions addresses the underlying causative factors. Exosome therapy, acknowledged for its relatively safe cell-free approach, emerges as a promising avenue. Notably, exosomes derived from stem cells exhibit comparable efficacy to their cellular counterparts. Nevertheless, extant methodologies for exosome production exhibit several limitations, particularly in achieving high-caliber, large-scale manufacturing. Consequently, this review is dedicated to elucidating the ongoing research endeavors and advancements of exosome therapy pertaining to the female reproductive aging.http://www.sciencedirect.com/science/article/pii/S2773041724000039Female reproductiveExosome therapyAging
spellingShingle Mengtong Zhang
Sichen Zhang
Shaowei Wang
Exosome therapy in female reproductive aging
Extracellular Vesicle
Female reproductive
Exosome therapy
Aging
title Exosome therapy in female reproductive aging
title_full Exosome therapy in female reproductive aging
title_fullStr Exosome therapy in female reproductive aging
title_full_unstemmed Exosome therapy in female reproductive aging
title_short Exosome therapy in female reproductive aging
title_sort exosome therapy in female reproductive aging
topic Female reproductive
Exosome therapy
Aging
url http://www.sciencedirect.com/science/article/pii/S2773041724000039
work_keys_str_mv AT mengtongzhang exosometherapyinfemalereproductiveaging
AT sichenzhang exosometherapyinfemalereproductiveaging
AT shaoweiwang exosometherapyinfemalereproductiveaging