In silico approach in the development of structural analogues of resveratrol with improved distribution in the central nervous system

Resveratrol exerts neuroprotective effects that are not only due to anti inflammatory and antioxidant activity but also by launched biogenesis via sirtuin-1 (SIRT1) protein that protects cells from oxidative stress. Resveratrol has low bioavailability due to low aqueous solubility and rapid metaboli...

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Bibliographic Details
Main Authors: Mitrović Darko, Pavlović Nebojša
Format: Article
Language:English
Published: University of Kragujevac, Faculty of Science 2024-01-01
Series:Kragujevac Journal of Science
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Online Access:https://scindeks-clanci.ceon.rs/data/pdf/1450-9636/2024/1450-96362401059M.pdf
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