Dapansutrile Regulates Mitochondrial Oxidative Stress and Reduces Hepatic Lipid Accumulation in Diabetic Mice

(1) Background: Hepatic lipid accumulation is the initial factor in metabolic-associated fatty liver disease (MAFLD) in type 2 diabetics, leading to accelerated liver damage. The NOD-like receptor protein 3 (NLRP3) inflammasome plays a critical role in this process. Dapansutrile (DAPA) is a novel NL...

Full description

Saved in:
Bibliographic Details
Main Authors: Ying Wu, Jiaqiang Zhou
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Current Issues in Molecular Biology
Subjects:
Online Access:https://www.mdpi.com/1467-3045/47/3/148
Tags: Add Tag
No Tags, Be the first to tag this record!