Differential correlations of refractive error, axial length, and axial length-to-corneal curvature ratio with anterior segment biometrics in myopic refractive surgery candidates
Purpose: To investigate the correlations of spherical equivalent (SE), axial length (AL), and AL to corneal curvature radius ratio (AL/CR) with anterior segment biometrics in candidates for myopic refractive surgery. Methods: Anterior segment biometrics of 2,478 myopic refractive surgery candidates...
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Elsevier
2024-12-01
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| Series: | Photodiagnosis and Photodynamic Therapy |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1572100024004459 |
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| author | Jian Zhang Youlin Zhu Ping Yuan Xiaojuan Dong Manyun Xie Zongrui Ma Rong Tian |
| author_facet | Jian Zhang Youlin Zhu Ping Yuan Xiaojuan Dong Manyun Xie Zongrui Ma Rong Tian |
| author_sort | Jian Zhang |
| collection | DOAJ |
| description | Purpose: To investigate the correlations of spherical equivalent (SE), axial length (AL), and AL to corneal curvature radius ratio (AL/CR) with anterior segment biometrics in candidates for myopic refractive surgery. Methods: Anterior segment biometrics of 2,478 myopic refractive surgery candidates measured by Pentacam were collected retrospectively. The anterior segment biometrics included anterior corneal curvature (ACC), posterior corneal curvature (PCC), white-to-white corneal diameter (WTW), central corneal thickness (CCT), corneal volume at 3 mm (CV), anterior corneal astigmatism (ACA), posterior corneal astigmatism (PCA), anterior corneal eccentricity (ACE), posterior corneal eccentricity (PCE), anterior corneal asphericity (ACAP), posterior corneal asphericity (PCAP), anterior chamber depth (ACD), and anterior chamber volume (ACV). The eyes were divided into four groups according to the AL: group 1, AL≤24 mm; group 2, 24mm<AL≤26 mm; group 3, 26mm<AL≤28 mm; group 4, AL≥28mm. The correlations between these biometrics with SE, AL, and AL/CR were assessed by Pearson or Spearman correlation tests. A correlation with a coefficient ≥0.3 and a p value <0.05 were considered significant. Results: In all AL groups, ACC was positively correlated with SE (r = 0.446 to 0.620) and negatively correlated with AL/CR (r = -0.704 to -0.894), whereas PCC was positively correlated with SE (r = 0.394 to 0.612) and negatively correlated with AL/CR (r = -0.606 to -0.787). WTW was positively correlated with SE (r = 0.304 to 0.474) in every group, and negatively correlated with AL/CR (r = -0.405 and -0.412) in group 1 and 4. ACA was positively correlated with AL (r = 0.310) and AL/CR (r = -0.333) in group 4. ACD was negatively correlated with AL (r = -0.304) in group 4, and positively correlated with AL/CR (r = -0.325) in group 2. ACV was positively correlated with SE (r = 0.344) in group 4, and positively correlated with AL (r = 0.303) in group 2. CCT, CV, PCA, ACE, PCE, ACAP, and PCAP was not significantly correlated with SE, AL, or AL/CR in any of group. Conclusions: Differential correlations were observed between anterior segment biometrics and SE, AL, and AL/CR, suggesting that various myopia indicators have different effects on ocular structures. These findings may help identify the ocular structures that can be targeted of refractive surgery. |
| format | Article |
| id | doaj-art-0c8180ee41024996a26e4f55a25f93e2 |
| institution | Kabale University |
| issn | 1572-1000 |
| language | English |
| publishDate | 2024-12-01 |
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| series | Photodiagnosis and Photodynamic Therapy |
| spelling | doaj-art-0c8180ee41024996a26e4f55a25f93e22024-12-13T10:56:16ZengElsevierPhotodiagnosis and Photodynamic Therapy1572-10002024-12-0150104408Differential correlations of refractive error, axial length, and axial length-to-corneal curvature ratio with anterior segment biometrics in myopic refractive surgery candidatesJian Zhang0Youlin Zhu1Ping Yuan2Xiaojuan Dong3Manyun Xie4Zongrui Ma5Rong Tian6Department of Ophthalmology, Changde Hospital, Xiangya School of Medicine, Central South University (The first people's hospital of Changde city), Changde, PR ChinaDepartment of Ophthalmology, Changde Hospital, Xiangya School of Medicine, Central South University (The first people's hospital of Changde city), Changde, PR ChinaDepartment of Ophthalmology, Changde Hospital, Xiangya School of Medicine, Central South University (The first people's hospital of Changde city), Changde, PR ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, PR ChinaDepartment of Ophthalmology, the Second Xiangya Hospital, Central South University, Hunan Clinical Research Center of Ophthalmic Disease, Changsha, PR ChinaRefractive Surgery Center, Changde Aier Eye Hospital, Changde, PR ChinaDepartment of Ophthalmology, Changde Hospital, Xiangya School of Medicine, Central South University (The first people's hospital of Changde city), Changde, PR China; Correspondence author at: Department of Ophthalmology, Changde Hospital, Xiangya School of Medicine, Central South University (The first people's hospital of Changde city), Changde, PR China, 18 Renmin Road, Wuling District, Changde City, 415000, Hunan Province, China.Purpose: To investigate the correlations of spherical equivalent (SE), axial length (AL), and AL to corneal curvature radius ratio (AL/CR) with anterior segment biometrics in candidates for myopic refractive surgery. Methods: Anterior segment biometrics of 2,478 myopic refractive surgery candidates measured by Pentacam were collected retrospectively. The anterior segment biometrics included anterior corneal curvature (ACC), posterior corneal curvature (PCC), white-to-white corneal diameter (WTW), central corneal thickness (CCT), corneal volume at 3 mm (CV), anterior corneal astigmatism (ACA), posterior corneal astigmatism (PCA), anterior corneal eccentricity (ACE), posterior corneal eccentricity (PCE), anterior corneal asphericity (ACAP), posterior corneal asphericity (PCAP), anterior chamber depth (ACD), and anterior chamber volume (ACV). The eyes were divided into four groups according to the AL: group 1, AL≤24 mm; group 2, 24mm<AL≤26 mm; group 3, 26mm<AL≤28 mm; group 4, AL≥28mm. The correlations between these biometrics with SE, AL, and AL/CR were assessed by Pearson or Spearman correlation tests. A correlation with a coefficient ≥0.3 and a p value <0.05 were considered significant. Results: In all AL groups, ACC was positively correlated with SE (r = 0.446 to 0.620) and negatively correlated with AL/CR (r = -0.704 to -0.894), whereas PCC was positively correlated with SE (r = 0.394 to 0.612) and negatively correlated with AL/CR (r = -0.606 to -0.787). WTW was positively correlated with SE (r = 0.304 to 0.474) in every group, and negatively correlated with AL/CR (r = -0.405 and -0.412) in group 1 and 4. ACA was positively correlated with AL (r = 0.310) and AL/CR (r = -0.333) in group 4. ACD was negatively correlated with AL (r = -0.304) in group 4, and positively correlated with AL/CR (r = -0.325) in group 2. ACV was positively correlated with SE (r = 0.344) in group 4, and positively correlated with AL (r = 0.303) in group 2. CCT, CV, PCA, ACE, PCE, ACAP, and PCAP was not significantly correlated with SE, AL, or AL/CR in any of group. Conclusions: Differential correlations were observed between anterior segment biometrics and SE, AL, and AL/CR, suggesting that various myopia indicators have different effects on ocular structures. These findings may help identify the ocular structures that can be targeted of refractive surgery.http://www.sciencedirect.com/science/article/pii/S1572100024004459MyopiaSpherical equivalentAxial lengthAxial length to corneal curvature radius ratioCorrelation |
| spellingShingle | Jian Zhang Youlin Zhu Ping Yuan Xiaojuan Dong Manyun Xie Zongrui Ma Rong Tian Differential correlations of refractive error, axial length, and axial length-to-corneal curvature ratio with anterior segment biometrics in myopic refractive surgery candidates Photodiagnosis and Photodynamic Therapy Myopia Spherical equivalent Axial length Axial length to corneal curvature radius ratio Correlation |
| title | Differential correlations of refractive error, axial length, and axial length-to-corneal curvature ratio with anterior segment biometrics in myopic refractive surgery candidates |
| title_full | Differential correlations of refractive error, axial length, and axial length-to-corneal curvature ratio with anterior segment biometrics in myopic refractive surgery candidates |
| title_fullStr | Differential correlations of refractive error, axial length, and axial length-to-corneal curvature ratio with anterior segment biometrics in myopic refractive surgery candidates |
| title_full_unstemmed | Differential correlations of refractive error, axial length, and axial length-to-corneal curvature ratio with anterior segment biometrics in myopic refractive surgery candidates |
| title_short | Differential correlations of refractive error, axial length, and axial length-to-corneal curvature ratio with anterior segment biometrics in myopic refractive surgery candidates |
| title_sort | differential correlations of refractive error axial length and axial length to corneal curvature ratio with anterior segment biometrics in myopic refractive surgery candidates |
| topic | Myopia Spherical equivalent Axial length Axial length to corneal curvature radius ratio Correlation |
| url | http://www.sciencedirect.com/science/article/pii/S1572100024004459 |
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