The microneme protein1 (MIC1) of Chinese 1 Toxoplasma regulates pyroptosis through the TLR4/NLRP3 pathway in macrophages

The microneme protein1 (MIC1) of Chinese 1 Toxoplasma regulates pyroptosis through the TLR4/NLRP3 pathway in macrophages

Abstract Background TgMIC1, a soluble adhesion protein that typically facilitates parasite invasion, exhibited varying expression levels among distinct virulence strains of Chinese 1 Toxoplasma. This study aims to explore its role in immunological regulation and its association with diverse postinfe...

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Bibliographic Details
Main Authors: Wenze Sun, Fan Zhang, Jinjin Zhu, Yanxia Yu, Yang Wang, Qingli Luo, Li Yu
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Parasites & Vectors
Subjects:
TgMIC1
Toxoplasma gondii
Pyrptosis
TLR4
NLRP3
Online Access:https://doi.org/10.1186/s13071-024-06584-z
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