Overexpression of ORP1C gene increases the rice resistance to Xanthomonas oryzae pv. oryzae through negatively regulating transcription activator-like effectors translocation

Bacterial leaf blight (BLB) caused by Xanthomonas oryzae pv. oryzae (Xoo) has shown a high incidence rate in rice fields in recent years. Rice resistance breeding is considered as the most effective method for achieving economical and sustainable management of BLB disease. The essential basis for re...

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Main Authors: Hongtao Ji, Lan Zhou, Ruibin Yang, Mingliang Xu, Hengjie Qian, Jingyi Tong, Mengjie Sun
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Plant Signaling & Behavior
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Online Access:http://dx.doi.org/10.1080/15592324.2024.2441864
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author Hongtao Ji
Lan Zhou
Ruibin Yang
Mingliang Xu
Hengjie Qian
Jingyi Tong
Mengjie Sun
author_facet Hongtao Ji
Lan Zhou
Ruibin Yang
Mingliang Xu
Hengjie Qian
Jingyi Tong
Mengjie Sun
author_sort Hongtao Ji
collection DOAJ
description Bacterial leaf blight (BLB) caused by Xanthomonas oryzae pv. oryzae (Xoo) has shown a high incidence rate in rice fields in recent years. Rice resistance breeding is considered as the most effective method for achieving economical and sustainable management of BLB disease. The essential basis for resistance breeding is rooted in the exploration of rice resistance genes and the clarification of the molecular mechanisms that underlie Xoo resistance. In our previous research, we showed that Xanthomonas outer protein XopZ and rice oxysterol-binding related protein ORP1C collaboratively regulate the compatible interaction between Xoo strain PXO99 and Nipponbare rice, but the deeper regulatory mechanisms remain unknown. In this study, we successfully constructed ORP1C overexpression rice using the plant binary expression vector pCAMBIA1301. Through a series of virulence and effector translocation detections in Xoo-rice interactions, we revealed that overexpression of the ORP1C gene largely increases rice resistance to multiple Xoo strains from different countries and regions. Mechanistically, ORP1C plays a Xoo resistant role through negatively regulating transcription activator-like effectors (TALEs) translocation, ORP1C has become a potential candidate gene resource for disease-resistant breeding in rice. Further studies also indicated that XopZ and ORP1C collaboratively regulate the compatible interaction of PXO99-Nipponbare by modulating TALEs translocation.
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spelling doaj-art-0c34d6dea88a42b38fe46c19fdb90cc12025-01-02T11:44:28ZengTaylor & Francis GroupPlant Signaling & Behavior1559-23242025-12-0120110.1080/15592324.2024.24418642441864Overexpression of ORP1C gene increases the rice resistance to Xanthomonas oryzae pv. oryzae through negatively regulating transcription activator-like effectors translocationHongtao Ji0Lan Zhou1Ruibin Yang2Mingliang Xu3Hengjie Qian4Jingyi Tong5Mengjie Sun6Jiangsu Normal UniversityJiangsu Normal UniversityJiangsu Normal UniversityJiangsu Normal UniversityJiangsu Normal UniversityJiangsu Normal UniversityJiangsu Normal UniversityBacterial leaf blight (BLB) caused by Xanthomonas oryzae pv. oryzae (Xoo) has shown a high incidence rate in rice fields in recent years. Rice resistance breeding is considered as the most effective method for achieving economical and sustainable management of BLB disease. The essential basis for resistance breeding is rooted in the exploration of rice resistance genes and the clarification of the molecular mechanisms that underlie Xoo resistance. In our previous research, we showed that Xanthomonas outer protein XopZ and rice oxysterol-binding related protein ORP1C collaboratively regulate the compatible interaction between Xoo strain PXO99 and Nipponbare rice, but the deeper regulatory mechanisms remain unknown. In this study, we successfully constructed ORP1C overexpression rice using the plant binary expression vector pCAMBIA1301. Through a series of virulence and effector translocation detections in Xoo-rice interactions, we revealed that overexpression of the ORP1C gene largely increases rice resistance to multiple Xoo strains from different countries and regions. Mechanistically, ORP1C plays a Xoo resistant role through negatively regulating transcription activator-like effectors (TALEs) translocation, ORP1C has become a potential candidate gene resource for disease-resistant breeding in rice. Further studies also indicated that XopZ and ORP1C collaboratively regulate the compatible interaction of PXO99-Nipponbare by modulating TALEs translocation.http://dx.doi.org/10.1080/15592324.2024.2441864xanthomonas oryzae pv. oryzaericeoxysterol-binding related protein orp1ctranscription activator-like effectors talestranslocation
spellingShingle Hongtao Ji
Lan Zhou
Ruibin Yang
Mingliang Xu
Hengjie Qian
Jingyi Tong
Mengjie Sun
Overexpression of ORP1C gene increases the rice resistance to Xanthomonas oryzae pv. oryzae through negatively regulating transcription activator-like effectors translocation
Plant Signaling & Behavior
xanthomonas oryzae pv. oryzae
rice
oxysterol-binding related protein orp1c
transcription activator-like effectors tales
translocation
title Overexpression of ORP1C gene increases the rice resistance to Xanthomonas oryzae pv. oryzae through negatively regulating transcription activator-like effectors translocation
title_full Overexpression of ORP1C gene increases the rice resistance to Xanthomonas oryzae pv. oryzae through negatively regulating transcription activator-like effectors translocation
title_fullStr Overexpression of ORP1C gene increases the rice resistance to Xanthomonas oryzae pv. oryzae through negatively regulating transcription activator-like effectors translocation
title_full_unstemmed Overexpression of ORP1C gene increases the rice resistance to Xanthomonas oryzae pv. oryzae through negatively regulating transcription activator-like effectors translocation
title_short Overexpression of ORP1C gene increases the rice resistance to Xanthomonas oryzae pv. oryzae through negatively regulating transcription activator-like effectors translocation
title_sort overexpression of orp1c gene increases the rice resistance to xanthomonas oryzae pv oryzae through negatively regulating transcription activator like effectors translocation
topic xanthomonas oryzae pv. oryzae
rice
oxysterol-binding related protein orp1c
transcription activator-like effectors tales
translocation
url http://dx.doi.org/10.1080/15592324.2024.2441864
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