APOC1 knockdown induces apoptosis and decreases angiogenesis in diffuse large B-cell lymphoma cells through blocking the PI3K/AKT/mTOR pathway

APOC1 knockdown induces apoptosis and decreases angiogenesis in diffuse large B-cell lymphoma cells through blocking the PI3K/AKT/mTOR pathway

Diffuse large B-cell lymphoma (DLBCL) is a highly heterogeneous metastatic lymphoma that can be treated by targeting angiogenesis. Apolipoprotein C1 (APOC1) plays a significant role in the proliferation and metastasis of various malignant tumors; however, its role in DLBCL—particularly its effects o...

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Bibliographic Details
Main Authors: Jing Gao, Xiaojuan Lu, Guanglei Wang, Tanling Huang, Zhongyu Tuo, Weiwei Meng
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2025-01-01
Series:Biomolecules & Biomedicine
Subjects:
Diffuse large B-cell lymphoma
DLBCL
Apolipoprotein C1
APOC1
human umbilical vein endothelial cells
HUVECs
Online Access:https://bjbms.org/ojs/index.php/bjbms/article/view/11550
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