Comparative Efficacy of Amiodarone and Lidocaine in Treating Cardiac Arrest Due to Ventricular Fibrillation and Pulseless Ventricular Tachycardia in Adults. A Literature Review
Introduction:Sudden cardiac arrest (SCA) is a critical emergency, with shockable rhythms like ventricular fibrillation (VF) and pulseless ventricular tachycardia (VT) posing challenges. Amiodarone and lidocaine are key antiarrhythmic drugs used with defibrillation. While both improve hospital admis...
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| Format: | Article |
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Kazimierz Wielki University
2024-12-01
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| Series: | Journal of Education, Health and Sport |
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| Online Access: | https://apcz.umk.pl/JEHS/article/view/56266 |
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| author | Patryk Dryja Agata Boczar Izabela Orzołek Izabela Stawicka Jakub Jarmołowicz Sven Solisch Bianka Solisch |
| author_facet | Patryk Dryja Agata Boczar Izabela Orzołek Izabela Stawicka Jakub Jarmołowicz Sven Solisch Bianka Solisch |
| author_sort | Patryk Dryja |
| collection | DOAJ |
| description |
Introduction:Sudden cardiac arrest (SCA) is a critical emergency, with shockable rhythms like ventricular fibrillation (VF) and pulseless ventricular tachycardia (VT) posing challenges. Amiodarone and lidocaine are key antiarrhythmic drugs used with defibrillation. While both improve hospital admission rates, their effects on survival and neurological outcomes remain unclear. This review examines their comparative efficacy to guide clinical practice.
Materials and methods:A thorough literature review was performed using electronic databases. The search was restricted to English-language articles published from 1970 to 2024.
Aim of the study:The aim of this study is to systematically review and compare the efficacy of lidocaine and amiodarone in the treatment of cardiac arrest due to ventricular fibrillation and ventricular tachycardia in adults. This review seeks to evaluate the existing literature to determine the effectiveness and clinical outcomes associated with each medication.
Conclusions: The comparative analysis of amiodarone and lidocaine highlights their respective strengths and limitations in managing cardiac arrest, offering valuable insights for clinical practice. Amiodarone stands out as the preferred antiarrhythmic agent due to its significant efficacy in improving short-term outcomes, such as return of spontaneous circulation (ROSC) and survival to hospital admission. Overall, amiodarone's efficacy and broader applicability position it as the first-line agent for shock-refractory ventricular fibrillation (VF) and pulseless ventricular tachycardia (pVT). Lidocaine serves as an important alternative in specific scenarios. Future research should aim to optimize antiarrhythmic protocols, improve long-term survival and neurological outcomes, and explore innovative approaches to resuscitation.
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| format | Article |
| id | doaj-art-0c2a4ecdc58d4ad7b0b8163becd88334 |
| institution | Kabale University |
| issn | 2391-8306 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj-art-0c2a4ecdc58d4ad7b0b8163becd883342024-12-11T08:02:24ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062024-12-017610.12775/JEHS.2024.76.56266Comparative Efficacy of Amiodarone and Lidocaine in Treating Cardiac Arrest Due to Ventricular Fibrillation and Pulseless Ventricular Tachycardia in Adults. A Literature ReviewPatryk Dryja0Agata Boczar1Izabela Orzołek2Izabela Stawicka3Jakub Jarmołowicz4Sven Solisch5Bianka Solisch6Opole University Hospital, al. W. Witosa 26 45-401 Wrocław University Hospital, ul. Borowska 213, 50-556 WrocławCzerniakowski Hospital, Stępińska 19/25, 00-739 WarsawCentral Clinical Hospital, Medical University of Warsaw, Stefana Banacha 1a, 02-097, WarsawWrocław University Hospital, ul. Borowska 213, 50-556 WrocławOpole University Hospital, al. W. Witosa 26 45-401 OpoleWrocław Medical University, wyb. Ludwika Pasteura 1, 50-367 Wrocław Introduction:Sudden cardiac arrest (SCA) is a critical emergency, with shockable rhythms like ventricular fibrillation (VF) and pulseless ventricular tachycardia (VT) posing challenges. Amiodarone and lidocaine are key antiarrhythmic drugs used with defibrillation. While both improve hospital admission rates, their effects on survival and neurological outcomes remain unclear. This review examines their comparative efficacy to guide clinical practice. Materials and methods:A thorough literature review was performed using electronic databases. The search was restricted to English-language articles published from 1970 to 2024. Aim of the study:The aim of this study is to systematically review and compare the efficacy of lidocaine and amiodarone in the treatment of cardiac arrest due to ventricular fibrillation and ventricular tachycardia in adults. This review seeks to evaluate the existing literature to determine the effectiveness and clinical outcomes associated with each medication. Conclusions: The comparative analysis of amiodarone and lidocaine highlights their respective strengths and limitations in managing cardiac arrest, offering valuable insights for clinical practice. Amiodarone stands out as the preferred antiarrhythmic agent due to its significant efficacy in improving short-term outcomes, such as return of spontaneous circulation (ROSC) and survival to hospital admission. Overall, amiodarone's efficacy and broader applicability position it as the first-line agent for shock-refractory ventricular fibrillation (VF) and pulseless ventricular tachycardia (pVT). Lidocaine serves as an important alternative in specific scenarios. Future research should aim to optimize antiarrhythmic protocols, improve long-term survival and neurological outcomes, and explore innovative approaches to resuscitation. https://apcz.umk.pl/JEHS/article/view/56266lidocaineamiodaroneVFpVTventricular fibrillationpulseless ventricular tachycardia |
| spellingShingle | Patryk Dryja Agata Boczar Izabela Orzołek Izabela Stawicka Jakub Jarmołowicz Sven Solisch Bianka Solisch Comparative Efficacy of Amiodarone and Lidocaine in Treating Cardiac Arrest Due to Ventricular Fibrillation and Pulseless Ventricular Tachycardia in Adults. A Literature Review Journal of Education, Health and Sport lidocaine amiodarone VF pVT ventricular fibrillation pulseless ventricular tachycardia |
| title | Comparative Efficacy of Amiodarone and Lidocaine in Treating Cardiac Arrest Due to Ventricular Fibrillation and Pulseless Ventricular Tachycardia in Adults. A Literature Review |
| title_full | Comparative Efficacy of Amiodarone and Lidocaine in Treating Cardiac Arrest Due to Ventricular Fibrillation and Pulseless Ventricular Tachycardia in Adults. A Literature Review |
| title_fullStr | Comparative Efficacy of Amiodarone and Lidocaine in Treating Cardiac Arrest Due to Ventricular Fibrillation and Pulseless Ventricular Tachycardia in Adults. A Literature Review |
| title_full_unstemmed | Comparative Efficacy of Amiodarone and Lidocaine in Treating Cardiac Arrest Due to Ventricular Fibrillation and Pulseless Ventricular Tachycardia in Adults. A Literature Review |
| title_short | Comparative Efficacy of Amiodarone and Lidocaine in Treating Cardiac Arrest Due to Ventricular Fibrillation and Pulseless Ventricular Tachycardia in Adults. A Literature Review |
| title_sort | comparative efficacy of amiodarone and lidocaine in treating cardiac arrest due to ventricular fibrillation and pulseless ventricular tachycardia in adults a literature review |
| topic | lidocaine amiodarone VF pVT ventricular fibrillation pulseless ventricular tachycardia |
| url | https://apcz.umk.pl/JEHS/article/view/56266 |
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