Molecular mechanism of β-arrestin 2 interaction with phosphorylated intracellular loop 3 of dopamine receptor D2

Abstract G protein-coupled receptors (GPCRs), the key regulators of cellular signaling, transduce signals through G proteins or arrestins. G protein- or arrestin-mediated signal transduction induces distinct functional consequences, and therefore the molecular mechanisms of the interaction between G...

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Bibliographic Details
Main Authors: Kiae Kim, Jeong Seok Ji, Hee Ryung Kim, Yoonjung Choi, Hyung Ho Lee, Asuka Inoue, Ka Young Chung
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08649-w
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