Increased prevalence of recurrence in squamous cell carcinoma arising from buccal mucosa: A pervasive threat requiring multidimensional perspectives

Perspective goal: Squamous cell carcinoma (SCC) of the buccal mucosa is at a higher risk of local recurrence. Surgery in this area is complex and frequently results in close or positive margins, which increases the risk of recurrence. A margin distance of less than 1 mm from the tumour is linked to...

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Main Authors: Thilaga Duraisamy, Ramya Ramadoss, Suganya Panneer Selvam, Sandhya Sundar, Nitya Krishnasamy, Hemashree
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Oral Oncology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2772906024003169
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author Thilaga Duraisamy
Ramya Ramadoss
Suganya Panneer Selvam
Sandhya Sundar
Nitya Krishnasamy
Hemashree
author_facet Thilaga Duraisamy
Ramya Ramadoss
Suganya Panneer Selvam
Sandhya Sundar
Nitya Krishnasamy
Hemashree
author_sort Thilaga Duraisamy
collection DOAJ
description Perspective goal: Squamous cell carcinoma (SCC) of the buccal mucosa is at a higher risk of local recurrence. Surgery in this area is complex and frequently results in close or positive margins, which increases the risk of recurrence. A margin distance of less than 1 mm from the tumour is linked to a higher rate of recurrence. Discussion: Anatomic, genetic, environmental, and lifestyle factors contribute to its resurgence. Effective prevention strategies, early detection, and treatment require a multidimensional approach. Understanding genetic, environmental, and socio-cultural factors can help develop effective prevention strategies, improve early detection, and enhance treatment outcomes. Conclusion: Despite advancements in medical technology and awareness campaigns, the aggressive nature of SCC and its adverse impact on patient's quality of life necessitates a comprehensive understanding of its factors. A comprehensive and multidimensional approach is crucial for combating this pervasive public health threat. By integrating this knowledge into prevention strategies, healthcare professionals can work towards reducing the burden of SCC and enhancing patients' quality of life.
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institution Kabale University
issn 2772-9060
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publishDate 2024-06-01
publisher Elsevier
record_format Article
series Oral Oncology Reports
spelling doaj-art-0c08f69ff86b4ffba4dc40d33d85d1382025-01-09T06:16:25ZengElsevierOral Oncology Reports2772-90602024-06-0110100470Increased prevalence of recurrence in squamous cell carcinoma arising from buccal mucosa: A pervasive threat requiring multidimensional perspectivesThilaga Duraisamy0Ramya Ramadoss1Suganya Panneer Selvam2Sandhya Sundar3Nitya Krishnasamy4 Hemashree5Department of Oral Biology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, 600077, IndiaCorresponding author.Department of Oral Pathology & Oral Biology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, 600077, India.; Department of Oral Biology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, 600077, IndiaDepartment of Oral Biology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, 600077, IndiaDepartment of Oral Biology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, 600077, IndiaDepartment of Oral Biology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, 600077, IndiaDepartment of Oral Biology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, 600077, IndiaPerspective goal: Squamous cell carcinoma (SCC) of the buccal mucosa is at a higher risk of local recurrence. Surgery in this area is complex and frequently results in close or positive margins, which increases the risk of recurrence. A margin distance of less than 1 mm from the tumour is linked to a higher rate of recurrence. Discussion: Anatomic, genetic, environmental, and lifestyle factors contribute to its resurgence. Effective prevention strategies, early detection, and treatment require a multidimensional approach. Understanding genetic, environmental, and socio-cultural factors can help develop effective prevention strategies, improve early detection, and enhance treatment outcomes. Conclusion: Despite advancements in medical technology and awareness campaigns, the aggressive nature of SCC and its adverse impact on patient's quality of life necessitates a comprehensive understanding of its factors. A comprehensive and multidimensional approach is crucial for combating this pervasive public health threat. By integrating this knowledge into prevention strategies, healthcare professionals can work towards reducing the burden of SCC and enhancing patients' quality of life.http://www.sciencedirect.com/science/article/pii/S2772906024003169
spellingShingle Thilaga Duraisamy
Ramya Ramadoss
Suganya Panneer Selvam
Sandhya Sundar
Nitya Krishnasamy
Hemashree
Increased prevalence of recurrence in squamous cell carcinoma arising from buccal mucosa: A pervasive threat requiring multidimensional perspectives
Oral Oncology Reports
title Increased prevalence of recurrence in squamous cell carcinoma arising from buccal mucosa: A pervasive threat requiring multidimensional perspectives
title_full Increased prevalence of recurrence in squamous cell carcinoma arising from buccal mucosa: A pervasive threat requiring multidimensional perspectives
title_fullStr Increased prevalence of recurrence in squamous cell carcinoma arising from buccal mucosa: A pervasive threat requiring multidimensional perspectives
title_full_unstemmed Increased prevalence of recurrence in squamous cell carcinoma arising from buccal mucosa: A pervasive threat requiring multidimensional perspectives
title_short Increased prevalence of recurrence in squamous cell carcinoma arising from buccal mucosa: A pervasive threat requiring multidimensional perspectives
title_sort increased prevalence of recurrence in squamous cell carcinoma arising from buccal mucosa a pervasive threat requiring multidimensional perspectives
url http://www.sciencedirect.com/science/article/pii/S2772906024003169
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