Vientiane Multigenerational Birth Cohort Project in Lao People’s Democratic Republic: Protocol for Establishing a Longitudinal Multigenerational Birth Cohort to Promote Population Health
BackgroundRapid global population growth and urbanization have led to an increase in urban populations in low- and middle-income countries. Although these urban areas have generally better health outcomes than lower-income rural areas, many environmental, social, and health c...
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JMIR Publications
2024-11-01
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| author | Jordyn T Wallenborn Miley Sinantha-Hu Vattahanaphone Ouipoulikoune Sengchanh Kounnavong Latsamy Siengsounthone Nicole Probst-Hensch Peter Odermatt Somphou Sayasone Günther Fink |
| author_facet | Jordyn T Wallenborn Miley Sinantha-Hu Vattahanaphone Ouipoulikoune Sengchanh Kounnavong Latsamy Siengsounthone Nicole Probst-Hensch Peter Odermatt Somphou Sayasone Günther Fink |
| author_sort | Jordyn T Wallenborn |
| collection | DOAJ |
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BackgroundRapid global population growth and urbanization have led to an increase in urban populations in low- and middle-income countries. Although these urban areas have generally better health outcomes than lower-income rural areas, many environmental, social, and health challenges remain. Vientiane, the capital of Lao People’s Democratic Republic (Lao PDR), has approximately 1.5 of the 7.5 million Laotian population (2022) and provides a unique opportunity to examine health outcomes among socioeconomically diverse populations in the rapidly urbanizing context of the country.
ObjectiveThe aim of the Vientiane multigenerational birth cohort (VITERBI) project is to (1) establish a multigenerational birth cohort in Vientiane capital, Lao PDR, which is representative of the local population, (2) serve as the basis for additional observational (ie, cross-sectional) and intervention studies that promote population health in Vientiane province, and (3) investigate the social, epidemiological, and medical problems of public health importance to Lao PDR.
MethodsVITERBI is a prospective multigenerational birth cohort. The study population is structured around children born between July 1, 2022, and June 30, 2023, who reside in Chanthabuly, Sikhottabong, Sangthong, or Mayparkngum districts of Vientiane. Whenever possible, children and their mothers are enrolled during pregnancy; nonreported pregnancies are enrolled after birth. The cohort plans to enroll 3000 pregnant women and their children and the infants’ fathers, grandparents, and great-grandparents for a total study population of approximately 13,000 individuals. Participants will be followed throughout the life course with a range of data collected, including demographics, behavior, diet, physical activity, physiology, neurodevelopment, health history, quality of life, environmental exposures, depression, anxiety, stress, resilience, household characteristics, obstetric history, birth outcomes, and various living and dementia scales for older adults. Biomarkers collected include height, weight, blood pressure, and hemoglobin levels. Currently, no statistical analyses are planned.
ResultsAs of April 2024, this study has enrolled 3500 pregnant women and 4579 family members. Study participation is ongoing until May 2025 at minimum, with the goal to extend follow-up until 2050.
ConclusionsThe study cohort will be used as a basis for further observational (cross-sectional, longitudinal) and intervention studies. It also serves as a tool to investigate social, epidemiological, and medical problems of public health importance to Lao PDR, which will contribute to broader understanding of regional and international contexts.
International Registered Report Identifier (IRRID)DERR1-10.2196/59545 |
| format | Article |
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| publishDate | 2024-11-01 |
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| spelling | doaj-art-0c05e6d6d72c40eba6f166a89c973f852024-11-27T17:30:31ZengJMIR PublicationsJMIR Research Protocols1929-07482024-11-0113e5954510.2196/59545Vientiane Multigenerational Birth Cohort Project in Lao People’s Democratic Republic: Protocol for Establishing a Longitudinal Multigenerational Birth Cohort to Promote Population HealthJordyn T Wallenbornhttps://orcid.org/0000-0003-4535-864XMiley Sinantha-Huhttps://orcid.org/0000-0002-4901-8821Vattahanaphone Ouipoulikounehttps://orcid.org/0009-0005-6318-3355Sengchanh Kounnavonghttps://orcid.org/0000-0001-5766-5941Latsamy Siengsounthonehttps://orcid.org/0000-0003-2233-977XNicole Probst-Henschhttps://orcid.org/0000-0001-8561-5976Peter Odermatthttps://orcid.org/0000-0002-0296-2508Somphou Sayasonehttps://orcid.org/0000-0001-8219-9567Günther Finkhttps://orcid.org/0000-0001-7525-3668 BackgroundRapid global population growth and urbanization have led to an increase in urban populations in low- and middle-income countries. Although these urban areas have generally better health outcomes than lower-income rural areas, many environmental, social, and health challenges remain. Vientiane, the capital of Lao People’s Democratic Republic (Lao PDR), has approximately 1.5 of the 7.5 million Laotian population (2022) and provides a unique opportunity to examine health outcomes among socioeconomically diverse populations in the rapidly urbanizing context of the country. ObjectiveThe aim of the Vientiane multigenerational birth cohort (VITERBI) project is to (1) establish a multigenerational birth cohort in Vientiane capital, Lao PDR, which is representative of the local population, (2) serve as the basis for additional observational (ie, cross-sectional) and intervention studies that promote population health in Vientiane province, and (3) investigate the social, epidemiological, and medical problems of public health importance to Lao PDR. MethodsVITERBI is a prospective multigenerational birth cohort. The study population is structured around children born between July 1, 2022, and June 30, 2023, who reside in Chanthabuly, Sikhottabong, Sangthong, or Mayparkngum districts of Vientiane. Whenever possible, children and their mothers are enrolled during pregnancy; nonreported pregnancies are enrolled after birth. The cohort plans to enroll 3000 pregnant women and their children and the infants’ fathers, grandparents, and great-grandparents for a total study population of approximately 13,000 individuals. Participants will be followed throughout the life course with a range of data collected, including demographics, behavior, diet, physical activity, physiology, neurodevelopment, health history, quality of life, environmental exposures, depression, anxiety, stress, resilience, household characteristics, obstetric history, birth outcomes, and various living and dementia scales for older adults. Biomarkers collected include height, weight, blood pressure, and hemoglobin levels. Currently, no statistical analyses are planned. ResultsAs of April 2024, this study has enrolled 3500 pregnant women and 4579 family members. Study participation is ongoing until May 2025 at minimum, with the goal to extend follow-up until 2050. ConclusionsThe study cohort will be used as a basis for further observational (cross-sectional, longitudinal) and intervention studies. It also serves as a tool to investigate social, epidemiological, and medical problems of public health importance to Lao PDR, which will contribute to broader understanding of regional and international contexts. International Registered Report Identifier (IRRID)DERR1-10.2196/59545https://www.researchprotocols.org/2024/1/e59545 |
| spellingShingle | Jordyn T Wallenborn Miley Sinantha-Hu Vattahanaphone Ouipoulikoune Sengchanh Kounnavong Latsamy Siengsounthone Nicole Probst-Hensch Peter Odermatt Somphou Sayasone Günther Fink Vientiane Multigenerational Birth Cohort Project in Lao People’s Democratic Republic: Protocol for Establishing a Longitudinal Multigenerational Birth Cohort to Promote Population Health JMIR Research Protocols |
| title | Vientiane Multigenerational Birth Cohort Project in Lao People’s Democratic Republic: Protocol for Establishing a Longitudinal Multigenerational Birth Cohort to Promote Population Health |
| title_full | Vientiane Multigenerational Birth Cohort Project in Lao People’s Democratic Republic: Protocol for Establishing a Longitudinal Multigenerational Birth Cohort to Promote Population Health |
| title_fullStr | Vientiane Multigenerational Birth Cohort Project in Lao People’s Democratic Republic: Protocol for Establishing a Longitudinal Multigenerational Birth Cohort to Promote Population Health |
| title_full_unstemmed | Vientiane Multigenerational Birth Cohort Project in Lao People’s Democratic Republic: Protocol for Establishing a Longitudinal Multigenerational Birth Cohort to Promote Population Health |
| title_short | Vientiane Multigenerational Birth Cohort Project in Lao People’s Democratic Republic: Protocol for Establishing a Longitudinal Multigenerational Birth Cohort to Promote Population Health |
| title_sort | vientiane multigenerational birth cohort project in lao people s democratic republic protocol for establishing a longitudinal multigenerational birth cohort to promote population health |
| url | https://www.researchprotocols.org/2024/1/e59545 |
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