Identification of a pancreatic stellate cell gene signature and lncRNA interactions associated with type 2 diabetes progression

Identification of a pancreatic stellate cell gene signature and lncRNA interactions associated with type 2 diabetes progression

BackgroundType 2 diabetes (T2D) has become a significant global health threat, yet its precise causes and mechanisms remain unclear. This study aims to identify gene expression patterns specific to T2D pancreatic islet cells and to explore the potential role of pancreatic stellate cells (PSCs) in T2...

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Bibliographic Details
Main Authors:	Jinjun Qiu, Peng Zhu, Xing Shi, Jinquan Xia, Shaowei Dong, Liqun Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Endocrinology
Subjects:	type 2 diabetes COL1A2hi/VCANhi/SULF1hi PSCs combined analysis gene expression profiling LncRNA-mRNA network immune microenvironment
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2024.1532609/full
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