Safety and efficacy of inpatient pulmonary rehabilitation for patients hospitalised with an acute exacerbation of chronic obstructive pulmonary disease: a systematic review protocol

Introduction Pulmonary rehabilitation (PR) following an acute exacerbation of chronic obstructive pulmonary disease (AECOPD) reduces the risk of hospital admissions, and improves physical function and health-related quality of life. However, the safety and efficacy of in-hospital PR during the most...

Full description

Saved in:
Bibliographic Details
Main Authors: Pat Camp, Kai Zhu, Jagdeep Gill, Ashley Kirkham, Joel Chen, Amy Ellis, Stephanie Crosbie, Holly Denson-Camp, Hannah Peters
Format: Article
Language:English
Published: BMJ Publishing Group 2021-06-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/11/6/e043377.full
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1846163736456331264
author Pat Camp
Kai Zhu
Jagdeep Gill
Ashley Kirkham
Joel Chen
Amy Ellis
Stephanie Crosbie
Holly Denson-Camp
Hannah Peters
author_facet Pat Camp
Kai Zhu
Jagdeep Gill
Ashley Kirkham
Joel Chen
Amy Ellis
Stephanie Crosbie
Holly Denson-Camp
Hannah Peters
author_sort Pat Camp
collection DOAJ
description Introduction Pulmonary rehabilitation (PR) following an acute exacerbation of chronic obstructive pulmonary disease (AECOPD) reduces the risk of hospital admissions, and improves physical function and health-related quality of life. However, the safety and efficacy of in-hospital PR during the most acute phase of an AECOPD is not well established. This paper describes the protocol for a systematic review with meta-analysis to determine the safety and efficacy of inpatient acute care PR during the hospitalisation phase.Methods and analysis Medical literature databases and registries MEDLINE, EMBASE, Physiotherapy Evidence Database, Cumulative Index to Nursing and Allied Health Literature, Canadian Agency for Drugs and Technologies in Health, CENTRAL, Allied and Complementary Medicine Database, WHO trials portal and ClinicalTrials.gov will be searched for articles from inception to June 2021 using a prespecified search strategy. We will identify randomised controlled trials that have a comparison of in-hospital PR with usual care. PR programmes had to commence during the hospitalisation and include a minimum of two sessions. Title and abstract followed by full-text screening will be conducted independently by two reviewers. A meta-analysis will be performed if there is sufficient homogeneity across selected studies or groups of studies. The Population, Intervention, Comparator, Outcomes and Study characteristics framework will be used to standardise the data collection process. The quality of the cumulative evidence will be assessed using the Grading of Recommendations, Assessment, Development and Evaluations framework.Ethics and dissemination AECOPD results in physical limitations which are amenable to PR. This review will assess the safety and efficacy of in-hospital PR for AECOPD. The results will be presented in a peer-reviewed publication and at research conferences. Ethical review is not required for this study.PROSPERO registration number CRD42021198877.
format Article
id doaj-art-0bb69903e03a4584b3898e9ed462618e
institution Kabale University
issn 2044-6055
language English
publishDate 2021-06-01
publisher BMJ Publishing Group
record_format Article
series BMJ Open
spelling doaj-art-0bb69903e03a4584b3898e9ed462618e2024-11-19T00:55:09ZengBMJ Publishing GroupBMJ Open2044-60552021-06-0111610.1136/bmjopen-2020-043377Safety and efficacy of inpatient pulmonary rehabilitation for patients hospitalised with an acute exacerbation of chronic obstructive pulmonary disease: a systematic review protocolPat Camp0Kai Zhu1Jagdeep Gill2Ashley Kirkham3Joel Chen4Amy Ellis5Stephanie Crosbie6Holly Denson-Camp7Hannah Peters8Faculty of Medicine, The University of British Columbia, Vancouver, British Columbia, CanadaFaculty of Medicine, The University of British Columbia, Vancouver, British Columbia, CanadaFaculty of Medicine, The University of British Columbia, Vancouver, British Columbia, CanadaCentre for Heart Lung Innovation, The University of British Columbia, Vancouver, British Columbia, CanadaCentre for Heart Lung Innovation, The University of British Columbia, Vancouver, British Columbia, CanadaSurrey Memorial Hospital, Fraser Health Authority, Surrey, British Columbia, CanadaS. Crosbie Consulting, Vancouver, British Columbia, CanadaCentre for Heart Lung Innovation, The University of British Columbia, Vancouver, British Columbia, CanadaFaculty of Medicine, The University of British Columbia, Vancouver, British Columbia, CanadaIntroduction Pulmonary rehabilitation (PR) following an acute exacerbation of chronic obstructive pulmonary disease (AECOPD) reduces the risk of hospital admissions, and improves physical function and health-related quality of life. However, the safety and efficacy of in-hospital PR during the most acute phase of an AECOPD is not well established. This paper describes the protocol for a systematic review with meta-analysis to determine the safety and efficacy of inpatient acute care PR during the hospitalisation phase.Methods and analysis Medical literature databases and registries MEDLINE, EMBASE, Physiotherapy Evidence Database, Cumulative Index to Nursing and Allied Health Literature, Canadian Agency for Drugs and Technologies in Health, CENTRAL, Allied and Complementary Medicine Database, WHO trials portal and ClinicalTrials.gov will be searched for articles from inception to June 2021 using a prespecified search strategy. We will identify randomised controlled trials that have a comparison of in-hospital PR with usual care. PR programmes had to commence during the hospitalisation and include a minimum of two sessions. Title and abstract followed by full-text screening will be conducted independently by two reviewers. A meta-analysis will be performed if there is sufficient homogeneity across selected studies or groups of studies. The Population, Intervention, Comparator, Outcomes and Study characteristics framework will be used to standardise the data collection process. The quality of the cumulative evidence will be assessed using the Grading of Recommendations, Assessment, Development and Evaluations framework.Ethics and dissemination AECOPD results in physical limitations which are amenable to PR. This review will assess the safety and efficacy of in-hospital PR for AECOPD. The results will be presented in a peer-reviewed publication and at research conferences. Ethical review is not required for this study.PROSPERO registration number CRD42021198877.https://bmjopen.bmj.com/content/11/6/e043377.full
spellingShingle Pat Camp
Kai Zhu
Jagdeep Gill
Ashley Kirkham
Joel Chen
Amy Ellis
Stephanie Crosbie
Holly Denson-Camp
Hannah Peters
Safety and efficacy of inpatient pulmonary rehabilitation for patients hospitalised with an acute exacerbation of chronic obstructive pulmonary disease: a systematic review protocol
BMJ Open
title Safety and efficacy of inpatient pulmonary rehabilitation for patients hospitalised with an acute exacerbation of chronic obstructive pulmonary disease: a systematic review protocol
title_full Safety and efficacy of inpatient pulmonary rehabilitation for patients hospitalised with an acute exacerbation of chronic obstructive pulmonary disease: a systematic review protocol
title_fullStr Safety and efficacy of inpatient pulmonary rehabilitation for patients hospitalised with an acute exacerbation of chronic obstructive pulmonary disease: a systematic review protocol
title_full_unstemmed Safety and efficacy of inpatient pulmonary rehabilitation for patients hospitalised with an acute exacerbation of chronic obstructive pulmonary disease: a systematic review protocol
title_short Safety and efficacy of inpatient pulmonary rehabilitation for patients hospitalised with an acute exacerbation of chronic obstructive pulmonary disease: a systematic review protocol
title_sort safety and efficacy of inpatient pulmonary rehabilitation for patients hospitalised with an acute exacerbation of chronic obstructive pulmonary disease a systematic review protocol
url https://bmjopen.bmj.com/content/11/6/e043377.full
work_keys_str_mv AT patcamp safetyandefficacyofinpatientpulmonaryrehabilitationforpatientshospitalisedwithanacuteexacerbationofchronicobstructivepulmonarydiseaseasystematicreviewprotocol
AT kaizhu safetyandefficacyofinpatientpulmonaryrehabilitationforpatientshospitalisedwithanacuteexacerbationofchronicobstructivepulmonarydiseaseasystematicreviewprotocol
AT jagdeepgill safetyandefficacyofinpatientpulmonaryrehabilitationforpatientshospitalisedwithanacuteexacerbationofchronicobstructivepulmonarydiseaseasystematicreviewprotocol
AT ashleykirkham safetyandefficacyofinpatientpulmonaryrehabilitationforpatientshospitalisedwithanacuteexacerbationofchronicobstructivepulmonarydiseaseasystematicreviewprotocol
AT joelchen safetyandefficacyofinpatientpulmonaryrehabilitationforpatientshospitalisedwithanacuteexacerbationofchronicobstructivepulmonarydiseaseasystematicreviewprotocol
AT amyellis safetyandefficacyofinpatientpulmonaryrehabilitationforpatientshospitalisedwithanacuteexacerbationofchronicobstructivepulmonarydiseaseasystematicreviewprotocol
AT stephaniecrosbie safetyandefficacyofinpatientpulmonaryrehabilitationforpatientshospitalisedwithanacuteexacerbationofchronicobstructivepulmonarydiseaseasystematicreviewprotocol
AT hollydensoncamp safetyandefficacyofinpatientpulmonaryrehabilitationforpatientshospitalisedwithanacuteexacerbationofchronicobstructivepulmonarydiseaseasystematicreviewprotocol
AT hannahpeters safetyandefficacyofinpatientpulmonaryrehabilitationforpatientshospitalisedwithanacuteexacerbationofchronicobstructivepulmonarydiseaseasystematicreviewprotocol