Exploring the impacts of senescence on implantation and early embryonic development using totipotent cell-derived blastoids
Introduction: Advanced maternal age is associated with reduced implantation and pregnancy rates, yet the underlying mechanisms remain poorly understood, and research models are limited. Objectives: Here, we aim to elucidate the impacts of senescence on implantation ability by employing blastoids to...
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Main Authors: | Yuxin Luo, Chenrui An, Ke Zhong, Ping Zhou, Dan Li, Hui Liu, Qing Guo, Wei Wei, Hen Pan, Zheying Min, Rong Li, Yang Yu, Yong Fan |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-02-01
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Series: | Journal of Advanced Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2090123224000730 |
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