Alantolactone mitigates the elevation of blood pressure in mice induced by angiotensin II by inhibiting calcium channel activation

Alantolactone mitigates the elevation of blood pressure in mice induced by angiotensin II by inhibiting calcium channel activation

Abstract Background The dried root of Inula helenium L., known as Inulae Radix in Mongolian medicine, is a widely used heat-clearing plant drug within the Asteraceae family. Alantolactone (ATL), a compound derived from Inulae Radix, is a sesquiterpene lactone with a range of biological activities. H...

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Bibliographic Details
Main Authors: Ruqiang Yuan, Mingjing Gao, Hu Xu, Qing Liang, Lei Qian, Yali Wang, Houli Zhang, Erjiao Qiang, Weijing Yun
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Cardiovascular Disorders
Subjects:
Alantolactone
Hypertension
Voltage-gated Calcium Channels
Calcium influx
Online Access:https://doi.org/10.1186/s12872-024-04461-2
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