Development and multi-cohort validation of a machine learning-based simplified frailty assessment tool for clinical risk prediction

Development and multi-cohort validation of a machine learning-based simplified frailty assessment tool for clinical risk prediction

Abstract Background Frailty significantly impacts health outcomes in aging populations, yet its routine assessment remains challenging due to the complexity and time-consuming nature of existing tools. This study aimed to develop and validate a clinically feasible, machine learning-based frailty ass...

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Bibliographic Details
Main Authors: Jiahui Lai, Cailian Cheng, Tiantian Liang, Leile Tang, Xinhua Guo, Xun Liu
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Journal of Translational Medicine
Subjects:
Frailty assessment
Machine learning
Chronic kidney disease
Cardiovascular risk
Mortality prediction
Risk stratification
Online Access:https://doi.org/10.1186/s12967-025-06728-4
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https://doi.org/10.1186/s12967-025-06728-4

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