Oral cancer immunology: state of the art and future perspectives
Abstract Oral cancer is a multifactorial disease involving genetic, epigenetic, and environmental factors. The literature indicates that inflammatory cells at the advancing front of the tumor induce a host immune response, preventing the spread of the tumor. However, cancer cells adopt various conti...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira de Pesquisa Odontológica
2024-12-01
|
| Series: | Brazilian Oral Research |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242024000106200&lng=en&tlng=en |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846118947499278336 |
|---|---|
| author | Fábio Muradás GIRARDI Lauren Frenzel SCHUCH Manoela Domingues MARTINS |
| author_facet | Fábio Muradás GIRARDI Lauren Frenzel SCHUCH Manoela Domingues MARTINS |
| author_sort | Fábio Muradás GIRARDI |
| collection | DOAJ |
| description | Abstract Oral cancer is a multifactorial disease involving genetic, epigenetic, and environmental factors. The literature indicates that inflammatory cells at the advancing front of the tumor induce a host immune response, preventing the spread of the tumor. However, cancer cells adopt various continued strategies to circumvent this immune surveillance. The complexity of immune mechanisms suggests that there must be virtually individual patterns of anti-tumor immune responses. Due to this important interaction of cancer with the immune system, the objective of the present study was to provide an up-to-date overview of immuno-oncology focused on oral cancer, summarizing the basic immunology, the classic risk factors, immunotherapy, and future treatment and prognostic perspectives. |
| format | Article |
| id | doaj-art-0b76c40d045a4991a34c3e2b70f9574a |
| institution | Kabale University |
| issn | 1807-3107 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Sociedade Brasileira de Pesquisa Odontológica |
| record_format | Article |
| series | Brazilian Oral Research |
| spelling | doaj-art-0b76c40d045a4991a34c3e2b70f9574a2024-12-17T08:03:13ZengSociedade Brasileira de Pesquisa OdontológicaBrazilian Oral Research1807-31072024-12-013810.1590/1807-3107bor-2024.vol38.0129Oral cancer immunology: state of the art and future perspectivesFábio Muradás GIRARDIhttps://orcid.org/0000-0001-9326-7780Lauren Frenzel SCHUCHhttps://orcid.org/0000-0002-0993-936XManoela Domingues MARTINShttps://orcid.org/0000-0001-8662-5965Abstract Oral cancer is a multifactorial disease involving genetic, epigenetic, and environmental factors. The literature indicates that inflammatory cells at the advancing front of the tumor induce a host immune response, preventing the spread of the tumor. However, cancer cells adopt various continued strategies to circumvent this immune surveillance. The complexity of immune mechanisms suggests that there must be virtually individual patterns of anti-tumor immune responses. Due to this important interaction of cancer with the immune system, the objective of the present study was to provide an up-to-date overview of immuno-oncology focused on oral cancer, summarizing the basic immunology, the classic risk factors, immunotherapy, and future treatment and prognostic perspectives.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242024000106200&lng=en&tlng=enMouth NeoplasmsCarcinogenesis |
| spellingShingle | Fábio Muradás GIRARDI Lauren Frenzel SCHUCH Manoela Domingues MARTINS Oral cancer immunology: state of the art and future perspectives Brazilian Oral Research Mouth Neoplasms Carcinogenesis |
| title | Oral cancer immunology: state of the art and future perspectives |
| title_full | Oral cancer immunology: state of the art and future perspectives |
| title_fullStr | Oral cancer immunology: state of the art and future perspectives |
| title_full_unstemmed | Oral cancer immunology: state of the art and future perspectives |
| title_short | Oral cancer immunology: state of the art and future perspectives |
| title_sort | oral cancer immunology state of the art and future perspectives |
| topic | Mouth Neoplasms Carcinogenesis |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242024000106200&lng=en&tlng=en |
| work_keys_str_mv | AT fabiomuradasgirardi oralcancerimmunologystateoftheartandfutureperspectives AT laurenfrenzelschuch oralcancerimmunologystateoftheartandfutureperspectives AT manoeladominguesmartins oralcancerimmunologystateoftheartandfutureperspectives |