Increased frontal [123I]FP-CIT binding in Parkinson’s disease patients with self-reported REM sleep behavior disorder

Increased frontal [123I]FP-CIT binding in Parkinson’s disease patients with self-reported REM sleep behavior disorder

Abstract Rapid eye movement (REM) sleep behavior disorder (RBD) is a frequent non-motor symptom of Parkinson’s disease (PD) and a potential early marker of synucleinopathy-related neurodegeneration. While striatal dopaminergic dysfunction in PD-RBD has been extensively studied, the role of extrastri...

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Main Authors: Elina Jaakkola, Jani Ijas, Juho Joutsa, Tero Vahlberg, Elina Myller, Mikael Eklund, Simo Nuuttila, Kirsi Murtomäki, Tuomas Mertsalmi, Reeta Levo, Tommi Noponen, Toni Ihalainen, Filip Scheperjans, Valtteri Kaasinen
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-025-01116-7
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