Association between HLA-DQB1, -DPB1 alleles and risk of carbamazepine-induced hypersensitivity reactions in Vietnamese patients with epilepsy

Association between HLA-DQB1, -DPB1 alleles and risk of carbamazepine-induced hypersensitivity reactions in Vietnamese patients with epilepsy

Adverse drug reactions are a serious problem for health and one of the main reasons for treatment failure with antiepileptic drugs. In this study, we determined the HLA-DQB1 and -DPB1 alleles in the blood samples of 44 epileptic patients receiving carbamazepine treatment, including 21 patients with...

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Bibliographic Details
Main Authors: Thi Thanh Nhan Le, Thi Tu Linh Nguyen, Lan Phuong Le, Doan Thuy Nguyen, Van Lieu Nguyen, Thi Van Anh Nguyen, Hong Thai Trinh
Format: Article
Language:English
Published: Vietnam Ministry of Science and Technology 2024-12-01
Series:Vietnam Journal of Science, Technology and Engineering
Subjects:
carbamazepine
epilepsy
HLA-DPB1
HLA-DQB1*03:03:02
Online Access:https://vietnamscience.vjst.vn/index.php/vjste/article/view/1244
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