Developmental regression of novel space preference in an autism spectrum disorder model is unlinked to GABAergic and social circuitry

Developmental regression of novel space preference in an autism spectrum disorder model is unlinked to GABAergic and social circuitry

Autism spectrum disorder (ASD) is characterized by social deficits and restricted behaviors, with developmental defects in GABAergic circuits proposed as a key underlying etiology. Here, we introduce the V-Y assay, a novel space preference test in which one arm of the Y-maze is initially hidden and...

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Bibliographic Details
Main Authors: Hirofumi Asano, Masaya Arai, Aito Narita, Takayuki Kuroiwa, Mamoru Fukuchi, Yuhei Yoshimoto, Soichi Oya, Goichi Miyoshi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cellular Neuroscience
Subjects:
GABAergic development
ASD model
novel space preference
regression
social behavior
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2024.1513347/full
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