The Comparison between Preoperative Maltodextrine and Sugar Water Administration on Random Blood Glucose Levels in Enhanced Recovery After Cesarean Surgery (ERACS) Patients

Background: Oral carbohydrate administration reduces post-operative insulin resistance and improves post-operative recovery. Sugar water and maltodextrin are oral carbohydrates that can be given to enhanced recovery after caesarean surgery (ERACS) patients. Objective: To compare the effect between...

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Main Authors: Satrio Adi Wicaksono, Dwi Pudjanarko, Ignatius Riwanto
Format: Article
Language:English
Published: Fakultas Kedokteran, Universitas Diponegoro 2024-11-01
Series:JAI (Jurnal Anestesiologi Indonesia)
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Online Access:https://ejournal.undip.ac.id/index.php/janesti/article/view/65043
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author Satrio Adi Wicaksono
Dwi Pudjanarko
Ignatius Riwanto
author_facet Satrio Adi Wicaksono
Dwi Pudjanarko
Ignatius Riwanto
author_sort Satrio Adi Wicaksono
collection DOAJ
description Background: Oral carbohydrate administration reduces post-operative insulin resistance and improves post-operative recovery. Sugar water and maltodextrin are oral carbohydrates that can be given to enhanced recovery after caesarean surgery (ERACS) patients. Objective: To compare the effect between pre-operative maltodextrin treatment and sugar water treatment on random blood glucose (RBG) levels in enhanced recovery after caesarean section (ERACS) patients. Methods: A randomized control study with pre-test and post-test design was used on 48 patients who underwent ERACS surgery at Dr. Kariadi hospital Semarang Indonesia and met the inclusion and exclusion criteria. Study subjects were divided into two groups: a pre-operative maltodextrin treatment group (n=24) and a pre-operative sugar water control group (n=24). RBG levels were checked with point-of-care testing (POCT) at soon before surgery and at 2 hours after surgery. Mann-Whitney test was used to analyse the difference of RBG levels between group with Maltodextrin and group with sugar water. Wilcoxon test was used to analyse the difference of RBG levels before surgery (pre-operative RBG) and 2 hours after surgery (post-operative RBG). The p value of <0.05 was considered as statistically significant. Result: There were significant lower RBG levels in group with pre-operative maltodextrin treatment compared to group with pre-operative sugar water at soon before surgery (pre-operative) (83.5 ± 9.73 vs 96.2 ± 12.99 mg/dL, p=0.003) and at 2 hours post-operative (101.7 ± 15.81 vs 118.9 ± 28.38, p=0.035) in ERACS patients. Conclusion: If confirmed by further studies, pre-operative maltodextrin administration might provide better outcome in reducing post-operative catabolic status by reducing post-operative insulin resistance and improving RBG levels before and after ERACS compared to sugar water control.
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spelling doaj-art-0adb8da2ce094812805a0f5e3027044d2024-12-16T06:18:52ZengFakultas Kedokteran, Universitas DiponegoroJAI (Jurnal Anestesiologi Indonesia)2337-51242089-970X2024-11-0116324124810.14710/jai.v0i0.6504324859The Comparison between Preoperative Maltodextrine and Sugar Water Administration on Random Blood Glucose Levels in Enhanced Recovery After Cesarean Surgery (ERACS) PatientsSatrio Adi Wicaksono0https://orcid.org/0000-0001-7937-4352Dwi Pudjanarko1Ignatius Riwanto2Doctoral Study Program in Medical and Health Sciences, Faculty of Medicine, Diponegoro University, Semarang, IndonesiaDoctoral Study Program in Medical and Health Sciences, Faculty of Medicine, Diponegoro University, Semarang, IndonesiaDoctoral Study Program in Medical and Health Sciences, Faculty of Medicine, Diponegoro University, Semarang, IndonesiaBackground: Oral carbohydrate administration reduces post-operative insulin resistance and improves post-operative recovery. Sugar water and maltodextrin are oral carbohydrates that can be given to enhanced recovery after caesarean surgery (ERACS) patients. Objective: To compare the effect between pre-operative maltodextrin treatment and sugar water treatment on random blood glucose (RBG) levels in enhanced recovery after caesarean section (ERACS) patients. Methods: A randomized control study with pre-test and post-test design was used on 48 patients who underwent ERACS surgery at Dr. Kariadi hospital Semarang Indonesia and met the inclusion and exclusion criteria. Study subjects were divided into two groups: a pre-operative maltodextrin treatment group (n=24) and a pre-operative sugar water control group (n=24). RBG levels were checked with point-of-care testing (POCT) at soon before surgery and at 2 hours after surgery. Mann-Whitney test was used to analyse the difference of RBG levels between group with Maltodextrin and group with sugar water. Wilcoxon test was used to analyse the difference of RBG levels before surgery (pre-operative RBG) and 2 hours after surgery (post-operative RBG). The p value of <0.05 was considered as statistically significant. Result: There were significant lower RBG levels in group with pre-operative maltodextrin treatment compared to group with pre-operative sugar water at soon before surgery (pre-operative) (83.5 ± 9.73 vs 96.2 ± 12.99 mg/dL, p=0.003) and at 2 hours post-operative (101.7 ± 15.81 vs 118.9 ± 28.38, p=0.035) in ERACS patients. Conclusion: If confirmed by further studies, pre-operative maltodextrin administration might provide better outcome in reducing post-operative catabolic status by reducing post-operative insulin resistance and improving RBG levels before and after ERACS compared to sugar water control.https://ejournal.undip.ac.id/index.php/janesti/article/view/65043carbohydratecaesarean surgeryeracsmaltodextrinrandom blood glucose
spellingShingle Satrio Adi Wicaksono
Dwi Pudjanarko
Ignatius Riwanto
The Comparison between Preoperative Maltodextrine and Sugar Water Administration on Random Blood Glucose Levels in Enhanced Recovery After Cesarean Surgery (ERACS) Patients
JAI (Jurnal Anestesiologi Indonesia)
carbohydrate
caesarean surgery
eracs
maltodextrin
random blood glucose
title The Comparison between Preoperative Maltodextrine and Sugar Water Administration on Random Blood Glucose Levels in Enhanced Recovery After Cesarean Surgery (ERACS) Patients
title_full The Comparison between Preoperative Maltodextrine and Sugar Water Administration on Random Blood Glucose Levels in Enhanced Recovery After Cesarean Surgery (ERACS) Patients
title_fullStr The Comparison between Preoperative Maltodextrine and Sugar Water Administration on Random Blood Glucose Levels in Enhanced Recovery After Cesarean Surgery (ERACS) Patients
title_full_unstemmed The Comparison between Preoperative Maltodextrine and Sugar Water Administration on Random Blood Glucose Levels in Enhanced Recovery After Cesarean Surgery (ERACS) Patients
title_short The Comparison between Preoperative Maltodextrine and Sugar Water Administration on Random Blood Glucose Levels in Enhanced Recovery After Cesarean Surgery (ERACS) Patients
title_sort comparison between preoperative maltodextrine and sugar water administration on random blood glucose levels in enhanced recovery after cesarean surgery eracs patients
topic carbohydrate
caesarean surgery
eracs
maltodextrin
random blood glucose
url https://ejournal.undip.ac.id/index.php/janesti/article/view/65043
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