The Relationship between Psychosocial Factors and Cognition in Multiple Sclerosis
Introduction. Multiple sclerosis (MS) is a common disorder in some regions of the world, with over 2.3 million people diagnosed worldwide. Cognitive impairment is one of the earliest symptoms to present in the course of the disease and can cause significant morbidity. We proposed a study to explore...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Behavioural Neurology |
| Online Access: | http://dx.doi.org/10.1155/2017/6847070 |
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| author | Fahad D. Alosaimi Alaa AlMulhem Mario Moscovici Hanan AlShalan Mohammad Alqazlan Abdulgader Aldaif Sanjeev Sockalingam |
| author_facet | Fahad D. Alosaimi Alaa AlMulhem Mario Moscovici Hanan AlShalan Mohammad Alqazlan Abdulgader Aldaif Sanjeev Sockalingam |
| author_sort | Fahad D. Alosaimi |
| collection | DOAJ |
| description | Introduction. Multiple sclerosis (MS) is a common disorder in some regions of the world, with over 2.3 million people diagnosed worldwide. Cognitive impairment is one of the earliest symptoms to present in the course of the disease and can cause significant morbidity. We proposed a study to explore the psychosocial predictors of cognitive impairment in MS patients in Saudi Arabia, a previously unexplored patient population. Methods. Demographic data, depression scale (PHQ9), symptom burden (PHQ15), anxiety (GAD7), disease duration, and Montreal Cognitive Assessment (MOCA) scores were collected from 195 patients in a neurology clinic in Ryiadh, Saudi Arabia. Univariate and multiple regression analyses were conducted to identify variables that are significantly associated with cognitive impairment. Results. Variables that were identified to be significantly associated with cognition, p<0.05, were education level, disease duration, and family history. Discussion. Both education level and disease duration were variables identified in previous studies. We showed family history to be a significant variable, and no association was found with depression or anxiety, which is unique to our study population. Conclusions. We identified several psychosocial predictors that are associated with cognition in our patient population. It was also noted that a difference exists between patient populations, highlighting the need for further studies in specific geographical regions. |
| format | Article |
| id | doaj-art-0a8f8b63e2c0480ea2432e0b33f0ad2d |
| institution | Kabale University |
| issn | 0953-4180 1875-8584 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Behavioural Neurology |
| spelling | doaj-art-0a8f8b63e2c0480ea2432e0b33f0ad2d2025-02-03T05:47:23ZengWileyBehavioural Neurology0953-41801875-85842017-01-01201710.1155/2017/68470706847070The Relationship between Psychosocial Factors and Cognition in Multiple SclerosisFahad D. Alosaimi0Alaa AlMulhem1Mario Moscovici2Hanan AlShalan3Mohammad Alqazlan4Abdulgader Aldaif5Sanjeev Sockalingam6Department of Psychiatry, King Saud University, Riyadh, Saudi ArabiaCollege of Medicine, King Saud University, Riyadh, Saudi ArabiaCentre for Mental Health, University Health Network, Department of Psychiatry, University of Toronto, Toronto, ON, CanadaCollege of Medicine, King Saud University, Riyadh, Saudi ArabiaDepartment of Mental Health, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi ArabiaDepartment of Neurology, King Saud University, Riyadh, Saudi ArabiaCentre for Mental Health, University Health Network, Department of Psychiatry, University of Toronto, Toronto, ON, CanadaIntroduction. Multiple sclerosis (MS) is a common disorder in some regions of the world, with over 2.3 million people diagnosed worldwide. Cognitive impairment is one of the earliest symptoms to present in the course of the disease and can cause significant morbidity. We proposed a study to explore the psychosocial predictors of cognitive impairment in MS patients in Saudi Arabia, a previously unexplored patient population. Methods. Demographic data, depression scale (PHQ9), symptom burden (PHQ15), anxiety (GAD7), disease duration, and Montreal Cognitive Assessment (MOCA) scores were collected from 195 patients in a neurology clinic in Ryiadh, Saudi Arabia. Univariate and multiple regression analyses were conducted to identify variables that are significantly associated with cognitive impairment. Results. Variables that were identified to be significantly associated with cognition, p<0.05, were education level, disease duration, and family history. Discussion. Both education level and disease duration were variables identified in previous studies. We showed family history to be a significant variable, and no association was found with depression or anxiety, which is unique to our study population. Conclusions. We identified several psychosocial predictors that are associated with cognition in our patient population. It was also noted that a difference exists between patient populations, highlighting the need for further studies in specific geographical regions.http://dx.doi.org/10.1155/2017/6847070 |
| spellingShingle | Fahad D. Alosaimi Alaa AlMulhem Mario Moscovici Hanan AlShalan Mohammad Alqazlan Abdulgader Aldaif Sanjeev Sockalingam The Relationship between Psychosocial Factors and Cognition in Multiple Sclerosis Behavioural Neurology |
| title | The Relationship between Psychosocial Factors and Cognition in Multiple Sclerosis |
| title_full | The Relationship between Psychosocial Factors and Cognition in Multiple Sclerosis |
| title_fullStr | The Relationship between Psychosocial Factors and Cognition in Multiple Sclerosis |
| title_full_unstemmed | The Relationship between Psychosocial Factors and Cognition in Multiple Sclerosis |
| title_short | The Relationship between Psychosocial Factors and Cognition in Multiple Sclerosis |
| title_sort | relationship between psychosocial factors and cognition in multiple sclerosis |
| url | http://dx.doi.org/10.1155/2017/6847070 |
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