Oxidative Stress in Dog with Heart Failure: The Role of Dietary Fatty Acids and Antioxidants

In dogs with heart failure, cell oxygenation and cellular metabolism do not work properly, leading to the production of a large amount of free radicals. In the organism, these free radicals are responsible of major cellular damages: this is oxidative stress. However, a suitable food intake plays an...

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Bibliographic Details
Main Authors: Emmanuelle Sagols, Nathalie Priymenko
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Veterinary Medicine International
Online Access:http://dx.doi.org/10.4061/2011/180206
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Summary:In dogs with heart failure, cell oxygenation and cellular metabolism do not work properly, leading to the production of a large amount of free radicals. In the organism, these free radicals are responsible of major cellular damages: this is oxidative stress. However, a suitable food intake plays an important role in limiting this phenomenon: on the one hand, the presence of essential fatty acids in the composition of membranes decreases sensitivity of cells to free radicals and constitutes a first protection against the oxidative stress; on the other hand, coenzyme Q10, vitamin E, and polyphenols are antioxidant molecules which can help cells to neutralize these free radicals.
ISSN:2042-0048