Chronic Prostatitis/Chronic Pelvic Pain Syndrome: Treatment Options with Neuromodulatory Pharmacotherapy and Acupuncture
Chronic prostatitis (CP)/chronic pelvic pain syndrome (CPPS) is a prevalent condition with complex pathogenesis, and the most effective treatment is still unknown. The negative impact of CP/CPPS on patient quality of life (QoL) is significant and represents a challenge for many clinicians. Additi...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sestre Milosrdnice University hospital, Institute of Clinical Medical Research
2024-01-01
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| Series: | Acta Clinica Croatica |
| Subjects: | |
| Online Access: | https://hrcak.srce.hr/file/467271 |
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| Summary: | Chronic prostatitis (CP)/chronic pelvic pain syndrome (CPPS) is a prevalent condition
with complex pathogenesis, and the most effective treatment is still unknown. The negative impact
of CP/CPPS on patient quality of life (QoL) is significant and represents a challenge for many
clinicians. Additionally, studies have indicated a potential association between prostatitis and prostate
cancer. Many pharmacologic and nonpharmacologic therapies have been utilized in everyday clinical
practice, but the majority have demonstrated limited effectiveness in reducing symptoms. Current “firstline”
pharmacology treatment options include antibiotics, anti-inflammatory, alpha-blockers, and 5-alpha
reductase inhibitors as monoterapy or their combination, despite the fact that systematic reviews
and meta-analyses show that many treatments for CP/CPPS are largely ineffective. Thus far, no highly
effective therapy has been identified, and treatment strategies have focused on symptomatic relief. Evidence
indicates that CP/CPPS may involve neuropathic pain to varying degrees, and neuromodulatory
pharmacotherapy and acupuncture could therefore be considered as potential treatments for cases that
are refractory to standard therapies. |
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| ISSN: | 0353-9466 1333-9451 |