Application of Patient Version of General Practitioner Assessment of Cognition for Screening Elderly with Mild Cognitive Impairment in Community
ObjectiveTo explore the application value of the patient version of general practitioner assessment of cognition (P-GPCOG) for screening elderly with mild cognitive impairment (MCI) in community.MethodsA total of 905 elderly were recruited from West China Tianfu Hospital, Sichuan University and Chon...
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Editorial Office of Rehabilitation Medicine
2024-08-01
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| Series: | 康复学报 |
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| Online Access: | http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2024.04010 |
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| author | YANG Ting HE Jiali SONG Linlin LIU Wentao GUI Chenfan CHEN Xiao XU Li JIA Chengsen |
| author_facet | YANG Ting HE Jiali SONG Linlin LIU Wentao GUI Chenfan CHEN Xiao XU Li JIA Chengsen |
| author_sort | YANG Ting |
| collection | DOAJ |
| description | ObjectiveTo explore the application value of the patient version of general practitioner assessment of cognition (P-GPCOG) for screening elderly with mild cognitive impairment (MCI) in community.MethodsA total of 905 elderly were recruited from West China Tianfu Hospital, Sichuan University and Chongzhou Second Hospital from April 2022 to November 2023, including 627 cases in normal cognitive function group (NC group) and 278 cases in MCI group. The cognitive function of the subjects was evaluated by P-GPCOG, the Montreal Cognitive Assessment (MoCA), and the 8-item ascertain dementia (AD8). The independence of daily living ability was evaluated by the Lawton Instrumental Activities of Daily Living Scale (IADLs). The Geriatric Depression Scale-15 (GDS-15) was used to assess the depressive symptoms of the subjects. The receiver operating characteristic (ROC) curve was drawn, and the area under the curve (AUC), sensitivity, specificity, positive predictive value and negative predictive value were calculated to evaluate the application value of GPCOG screening.ResultsCompared with the NC group, the MoCA and Lawton-IADL scores were significantly lower in the MCI group (<italic>P</italic><0.001, <italic>P</italic>=0.022). The AD8 and GDS-15 scores were significantly higher (<italic>P</italic><0.001). There was a significant difference in the P-GPCOG scores between the two groups (<italic>Z</italic>=15.001, <italic>P</italic><0.001). Compared with the NC group, correct rate of the time orientation, clock drawing, reporting events and delayed recall, and the total score were significantly lower in the MCI group, with statistically significant differences (<italic>P</italic><0.001). In the MCI group, the order of cognitive impairment rate from high to low was delayed recall test, clock drawing test, time orientation and reporting events. AUC of P-GPCOG for differentiating MCI patients was 0.804 [95% <italic>CI</italic> (0.773, 0.836), <italic>P</italic><0.001], with an optimal cutoff value of 7/8 points. The sensitivity was 82.7%, the specificity was 72.6%, the positive predictive value was 57.2%, and the negative predictive value was 90.4%.ConclusionThe P-GPCOG is a good community-based cognitive screening tool for screening MCI patients in community, but its original scoring criteria needs to be refined to improve the correct screening rate. |
| format | Article |
| id | doaj-art-0a5421e3479944c0b87b8d87cef1dbd8 |
| institution | Kabale University |
| issn | 2096-0328 |
| language | English |
| publishDate | 2024-08-01 |
| publisher | Editorial Office of Rehabilitation Medicine |
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| series | 康复学报 |
| spelling | doaj-art-0a5421e3479944c0b87b8d87cef1dbd82025-01-14T10:09:03ZengEditorial Office of Rehabilitation Medicine康复学报2096-03282024-08-013437738265672433Application of Patient Version of General Practitioner Assessment of Cognition for Screening Elderly with Mild Cognitive Impairment in CommunityYANG TingHE JialiSONG LinlinLIU WentaoGUI ChenfanCHEN XiaoXU LiJIA ChengsenObjectiveTo explore the application value of the patient version of general practitioner assessment of cognition (P-GPCOG) for screening elderly with mild cognitive impairment (MCI) in community.MethodsA total of 905 elderly were recruited from West China Tianfu Hospital, Sichuan University and Chongzhou Second Hospital from April 2022 to November 2023, including 627 cases in normal cognitive function group (NC group) and 278 cases in MCI group. The cognitive function of the subjects was evaluated by P-GPCOG, the Montreal Cognitive Assessment (MoCA), and the 8-item ascertain dementia (AD8). The independence of daily living ability was evaluated by the Lawton Instrumental Activities of Daily Living Scale (IADLs). The Geriatric Depression Scale-15 (GDS-15) was used to assess the depressive symptoms of the subjects. The receiver operating characteristic (ROC) curve was drawn, and the area under the curve (AUC), sensitivity, specificity, positive predictive value and negative predictive value were calculated to evaluate the application value of GPCOG screening.ResultsCompared with the NC group, the MoCA and Lawton-IADL scores were significantly lower in the MCI group (<italic>P</italic><0.001, <italic>P</italic>=0.022). The AD8 and GDS-15 scores were significantly higher (<italic>P</italic><0.001). There was a significant difference in the P-GPCOG scores between the two groups (<italic>Z</italic>=15.001, <italic>P</italic><0.001). Compared with the NC group, correct rate of the time orientation, clock drawing, reporting events and delayed recall, and the total score were significantly lower in the MCI group, with statistically significant differences (<italic>P</italic><0.001). In the MCI group, the order of cognitive impairment rate from high to low was delayed recall test, clock drawing test, time orientation and reporting events. AUC of P-GPCOG for differentiating MCI patients was 0.804 [95% <italic>CI</italic> (0.773, 0.836), <italic>P</italic><0.001], with an optimal cutoff value of 7/8 points. The sensitivity was 82.7%, the specificity was 72.6%, the positive predictive value was 57.2%, and the negative predictive value was 90.4%.ConclusionThe P-GPCOG is a good community-based cognitive screening tool for screening MCI patients in community, but its original scoring criteria needs to be refined to improve the correct screening rate.http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2024.04010mild cognitive impairmentpatient version of general practitioner assessment of cognitioncognitive screeningsensitivityspecificity |
| spellingShingle | YANG Ting HE Jiali SONG Linlin LIU Wentao GUI Chenfan CHEN Xiao XU Li JIA Chengsen Application of Patient Version of General Practitioner Assessment of Cognition for Screening Elderly with Mild Cognitive Impairment in Community 康复学报 mild cognitive impairment patient version of general practitioner assessment of cognition cognitive screening sensitivity specificity |
| title | Application of Patient Version of General Practitioner Assessment of Cognition for Screening Elderly with Mild Cognitive Impairment in Community |
| title_full | Application of Patient Version of General Practitioner Assessment of Cognition for Screening Elderly with Mild Cognitive Impairment in Community |
| title_fullStr | Application of Patient Version of General Practitioner Assessment of Cognition for Screening Elderly with Mild Cognitive Impairment in Community |
| title_full_unstemmed | Application of Patient Version of General Practitioner Assessment of Cognition for Screening Elderly with Mild Cognitive Impairment in Community |
| title_short | Application of Patient Version of General Practitioner Assessment of Cognition for Screening Elderly with Mild Cognitive Impairment in Community |
| title_sort | application of patient version of general practitioner assessment of cognition for screening elderly with mild cognitive impairment in community |
| topic | mild cognitive impairment patient version of general practitioner assessment of cognition cognitive screening sensitivity specificity |
| url | http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2024.04010 |
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