A scientometric study on research characteristics and trends of amyloidosis involving the oral cavity

Background/purpose: Oral involvement often constitutes the first sign of amyloidosis as a life-threatening disease that can lead to multiple organ impairment. The purpose of this study was to analyze the scientometric characteristics and research trends of amyloidosis involving the oral cavity. Mate...

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Main Authors: Wei Liu, Cheng Jiang, Xuemin Shen, Yunteng Wu, Jie Wei
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Journal of Dental Sciences
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Online Access:http://www.sciencedirect.com/science/article/pii/S1991790224004392
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author Wei Liu
Cheng Jiang
Xuemin Shen
Yunteng Wu
Jie Wei
author_facet Wei Liu
Cheng Jiang
Xuemin Shen
Yunteng Wu
Jie Wei
author_sort Wei Liu
collection DOAJ
description Background/purpose: Oral involvement often constitutes the first sign of amyloidosis as a life-threatening disease that can lead to multiple organ impairment. The purpose of this study was to analyze the scientometric characteristics and research trends of amyloidosis involving the oral cavity. Materials and methods: All the papers on oral involvement of amyloidosis were comprehensively retrieved from the Scopus database. The years of publication were divided into before 2015 and 2015–2024 in the analysis of research trends. Results: There were 2540 relevant papers on amyloidosis involving the oral cavity, with total citations of 73,896 and the h index of 119. The related disorders were light chain amyloidosis, transthyretin amyloidosis, amyloid A amyloidosis, heart/cardiac amyloidosis, cardiomyopathy, kidney amyloidosis, and multiple myeloma. The trend of drug aspect, e.g. prednisone, colchicine, corticosteroid, doxorubicin, and vincristine before 2015 has changed to monoclonal antibody, daratumumab, tafamidis, proteasome inhibitor, carfilzomib, ixazomib, patisiran, pomalidomide, diflunisal, and doxycycline. Besides, the trend of clinical aspect has changed to complication, quality of life, risk factor, diagnostic imaging, prospective study, and early diagnosis after 2015. Herein, we highlight the awareness of early diagnosis and improve the access to care for amyloidosis, since oral involvement frequently constitutes the first sign of this disease. Conclusion: This scientometric study elucidated the current scenario and research trends of amyloidosis, underpinning that stomatologists can play roles in providing early recognition and timely diagnosis of amyloidosis when it involved the oral cavity.
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spelling doaj-art-0a3a53d9b7cd4d359a4e80df4e69974f2025-08-20T03:44:28ZengElsevierJournal of Dental Sciences1991-79022025-04-012021257126110.1016/j.jds.2024.12.010A scientometric study on research characteristics and trends of amyloidosis involving the oral cavityWei Liu0Cheng Jiang1Xuemin Shen2Yunteng Wu3Jie Wei4Department of Stomatology, Fengcheng Hospital of Fengxian District, Shanghai Ninth People's Hospital Fengcheng Branch Hospital, Shanghai, China; Department of Oral and Maxillofacial-Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; College of Stomatology, Shanghai Jiao Tong University, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, ChinaDepartment of Stomatology, Hangzhou Red Cross Hospital, Zhejiang Hospital of Integrated Traditional Chinese and Western Medicine, Hangzhou, Zhejiang, ChinaCollege of Stomatology, Shanghai Jiao Tong University, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China; Department of Oral Mucosal Diseases, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Oral and Maxillofacial-Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; College of Stomatology, Shanghai Jiao Tong University, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China; Corresponding author. Department of Oral and Maxillofacial-Head and Neck Oncology, Shanghai Ninth People's Hospital, 500 Quxi Road, Shanghai 200011, China.Department of Stomatology, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Corresponding author. Department of Stomatology, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, Shanghai 200092, China.Background/purpose: Oral involvement often constitutes the first sign of amyloidosis as a life-threatening disease that can lead to multiple organ impairment. The purpose of this study was to analyze the scientometric characteristics and research trends of amyloidosis involving the oral cavity. Materials and methods: All the papers on oral involvement of amyloidosis were comprehensively retrieved from the Scopus database. The years of publication were divided into before 2015 and 2015–2024 in the analysis of research trends. Results: There were 2540 relevant papers on amyloidosis involving the oral cavity, with total citations of 73,896 and the h index of 119. The related disorders were light chain amyloidosis, transthyretin amyloidosis, amyloid A amyloidosis, heart/cardiac amyloidosis, cardiomyopathy, kidney amyloidosis, and multiple myeloma. The trend of drug aspect, e.g. prednisone, colchicine, corticosteroid, doxorubicin, and vincristine before 2015 has changed to monoclonal antibody, daratumumab, tafamidis, proteasome inhibitor, carfilzomib, ixazomib, patisiran, pomalidomide, diflunisal, and doxycycline. Besides, the trend of clinical aspect has changed to complication, quality of life, risk factor, diagnostic imaging, prospective study, and early diagnosis after 2015. Herein, we highlight the awareness of early diagnosis and improve the access to care for amyloidosis, since oral involvement frequently constitutes the first sign of this disease. Conclusion: This scientometric study elucidated the current scenario and research trends of amyloidosis, underpinning that stomatologists can play roles in providing early recognition and timely diagnosis of amyloidosis when it involved the oral cavity.http://www.sciencedirect.com/science/article/pii/S1991790224004392AmyloidosisBibliometricsEarly diagnosisMacroglossiaOralTongue
spellingShingle Wei Liu
Cheng Jiang
Xuemin Shen
Yunteng Wu
Jie Wei
A scientometric study on research characteristics and trends of amyloidosis involving the oral cavity
Journal of Dental Sciences
Amyloidosis
Bibliometrics
Early diagnosis
Macroglossia
Oral
Tongue
title A scientometric study on research characteristics and trends of amyloidosis involving the oral cavity
title_full A scientometric study on research characteristics and trends of amyloidosis involving the oral cavity
title_fullStr A scientometric study on research characteristics and trends of amyloidosis involving the oral cavity
title_full_unstemmed A scientometric study on research characteristics and trends of amyloidosis involving the oral cavity
title_short A scientometric study on research characteristics and trends of amyloidosis involving the oral cavity
title_sort scientometric study on research characteristics and trends of amyloidosis involving the oral cavity
topic Amyloidosis
Bibliometrics
Early diagnosis
Macroglossia
Oral
Tongue
url http://www.sciencedirect.com/science/article/pii/S1991790224004392
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