Green Synthesis of Gold Nanoparticles Using Eucalyptus and Piper Longum and Antimicrobial Activity Evaluation

Background: Gold is the oldest dental restorative material, used for dental repairs for more than 4000 years, and remains an important metal included in the dental sector. In a world where nanoparticle importance has been well established and preparation of nanoparticles has become much easier, it i...

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Main Authors: Nadhirah Faiz, Vinay Sivaswamy, Subhashree Rohinikumar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Indian Journal of Dental Research
Subjects:
Online Access:https://journals.lww.com/10.4103/ijdr.ijdr_22_24
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author Nadhirah Faiz
Vinay Sivaswamy
Subhashree Rohinikumar
author_facet Nadhirah Faiz
Vinay Sivaswamy
Subhashree Rohinikumar
author_sort Nadhirah Faiz
collection DOAJ
description Background: Gold is the oldest dental restorative material, used for dental repairs for more than 4000 years, and remains an important metal included in the dental sector. In a world where nanoparticle importance has been well established and preparation of nanoparticles has become much easier, it is important to assess if these nanoparticles can be extracted from plants as well. Along with its extraction, analysis of each property of the nanoparticle is essential. Pepper and eucalyptus remain two of the most important ingredients used in ayurveda and can be easily found as a component in everyday consumption. Aim: This study was to extract gold nanoparticles using eucalyptus and piper longum and evaluate the antibacterial activity of the derived gold nanoparticles. Materials and Methodology: Preparation of plant extract was done following which extraction of gold nanoparticles was performed. Antibacterial properties of the gold nanoparticles were tested by well diffusion method and compared against the antibacterial gold standard, antibiotic amoxicillin. After 24 hours, the zone of inhibitions was measured in millimeters and the data were compiled. Results: The resultant green synthesized gold nanoparticles show high antibacterial activity against S. albicans, and a fair amount of antibacterial activity against S. mutans, S. aureus, and E. faecalis, which was revealed by comparing the zone of inhibition to the gold standard, amoxicillin 500 mg. Conclusion: Gold nanoparticles were found to have good antimicrobial activity.
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institution Kabale University
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1998-3603
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publisher Wolters Kluwer Medknow Publications
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series Indian Journal of Dental Research
spelling doaj-art-0a3a2c3b06fb41b9895a3a3a5ac2b8dd2025-08-20T03:53:38ZengWolters Kluwer Medknow PublicationsIndian Journal of Dental Research0970-92901998-36032025-01-0135442943210.4103/ijdr.ijdr_22_24Green Synthesis of Gold Nanoparticles Using Eucalyptus and Piper Longum and Antimicrobial Activity EvaluationNadhirah FaizVinay SivaswamySubhashree RohinikumarBackground: Gold is the oldest dental restorative material, used for dental repairs for more than 4000 years, and remains an important metal included in the dental sector. In a world where nanoparticle importance has been well established and preparation of nanoparticles has become much easier, it is important to assess if these nanoparticles can be extracted from plants as well. Along with its extraction, analysis of each property of the nanoparticle is essential. Pepper and eucalyptus remain two of the most important ingredients used in ayurveda and can be easily found as a component in everyday consumption. Aim: This study was to extract gold nanoparticles using eucalyptus and piper longum and evaluate the antibacterial activity of the derived gold nanoparticles. Materials and Methodology: Preparation of plant extract was done following which extraction of gold nanoparticles was performed. Antibacterial properties of the gold nanoparticles were tested by well diffusion method and compared against the antibacterial gold standard, antibiotic amoxicillin. After 24 hours, the zone of inhibitions was measured in millimeters and the data were compiled. Results: The resultant green synthesized gold nanoparticles show high antibacterial activity against S. albicans, and a fair amount of antibacterial activity against S. mutans, S. aureus, and E. faecalis, which was revealed by comparing the zone of inhibition to the gold standard, amoxicillin 500 mg. Conclusion: Gold nanoparticles were found to have good antimicrobial activity.https://journals.lww.com/10.4103/ijdr.ijdr_22_24antimicrobialeucalyptusextractgoldnanoparticles
spellingShingle Nadhirah Faiz
Vinay Sivaswamy
Subhashree Rohinikumar
Green Synthesis of Gold Nanoparticles Using Eucalyptus and Piper Longum and Antimicrobial Activity Evaluation
Indian Journal of Dental Research
antimicrobial
eucalyptus
extract
gold
nanoparticles
title Green Synthesis of Gold Nanoparticles Using Eucalyptus and Piper Longum and Antimicrobial Activity Evaluation
title_full Green Synthesis of Gold Nanoparticles Using Eucalyptus and Piper Longum and Antimicrobial Activity Evaluation
title_fullStr Green Synthesis of Gold Nanoparticles Using Eucalyptus and Piper Longum and Antimicrobial Activity Evaluation
title_full_unstemmed Green Synthesis of Gold Nanoparticles Using Eucalyptus and Piper Longum and Antimicrobial Activity Evaluation
title_short Green Synthesis of Gold Nanoparticles Using Eucalyptus and Piper Longum and Antimicrobial Activity Evaluation
title_sort green synthesis of gold nanoparticles using eucalyptus and piper longum and antimicrobial activity evaluation
topic antimicrobial
eucalyptus
extract
gold
nanoparticles
url https://journals.lww.com/10.4103/ijdr.ijdr_22_24
work_keys_str_mv AT nadhirahfaiz greensynthesisofgoldnanoparticlesusingeucalyptusandpiperlongumandantimicrobialactivityevaluation
AT vinaysivaswamy greensynthesisofgoldnanoparticlesusingeucalyptusandpiperlongumandantimicrobialactivityevaluation
AT subhashreerohinikumar greensynthesisofgoldnanoparticlesusingeucalyptusandpiperlongumandantimicrobialactivityevaluation