Prognostic factors of intracranial purulent-septic complications of combat-related gunshot penetrating skull and brain wounds.
Purpose – to analyze the structure of intracranial purulent-septic complications (IPSC), determine the factors influencing development of purulent-septic complications in patients with combat-related gunshot penetrating skull and brain wounds (CRPSBW), determine the effect of intracranial PSC on pa...
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| Format: | Article |
| Language: | English |
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Dnipro State Medical University
2019-11-01
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| Series: | Medičnì Perspektivi |
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| Online Access: | http://journals.uran.ua/index.php/2307-0404/article/view/181881 |
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| author | A. G. Sirko L. A. Dzyak G. S. Pylypenko I. O. Yovenko A. A. Skrypnik |
| author_facet | A. G. Sirko L. A. Dzyak G. S. Pylypenko I. O. Yovenko A. A. Skrypnik |
| author_sort | A. G. Sirko |
| collection | DOAJ |
| description | Purpose – to analyze the structure of intracranial purulent-septic complications (IPSC), determine the factors influencing development of purulent-septic complications in patients with combat-related gunshot penetrating skull and brain wounds (CRPSBW), determine the effect of intracranial PSC on patients’ outcomes. A prospective analysis of results of examination and treatment of 121 patients was performed. All patients had gunshot penetrating skull and brain wounds sustained in combat conditions during a local armed conflict in the Eastern Ukraine. Evaluation of treatment outcome included analysis of mortality in 1 month (survived/died) and dichotomous Glasgow Outcome Scale (GOS) score in 12 months (favorable/unfavorable outcome). 121 wounded men aged 18 to 56 (average, 34.1±9.1) were included in the study. Intracranial purulent-septic complications (IPSC) were diagnosed in 14 (11.6%) gunshot CRPSBW patients. The following prognostic factors had statistically significantly correlation with the risk of intracranial purulent-septic complications development: wound liquorrhea on admission (p = 0.043), intraventricular hemorrhage (p = 0.007), bone fragments left in the wound (p = 0.0152), and duration of inflow-outflow wound drainage for more than 3 days (p= 0.0123). Intracranial PSC patients had mortality rate of 50%, and only 14.3% of those patients had a favorable outcome according to GOS score in one year. Presence of intracranial PSC had statistically significant association with mortality rate (p=0.0091) and GOS score in one year (p=0.0001). |
| format | Article |
| id | doaj-art-0a33ff2c9066422694bf1215a5efe79a |
| institution | Kabale University |
| issn | 2307-0404 |
| language | English |
| publishDate | 2019-11-01 |
| publisher | Dnipro State Medical University |
| record_format | Article |
| series | Medičnì Perspektivi |
| spelling | doaj-art-0a33ff2c9066422694bf1215a5efe79a2024-12-02T03:03:54ZengDnipro State Medical UniversityMedičnì Perspektivi2307-04042019-11-01243586610.26641/2307-0404.2019.3.181881181881Prognostic factors of intracranial purulent-septic complications of combat-related gunshot penetrating skull and brain wounds.A. G. SirkoL. A. DzyakG. S. PylypenkoI. O. YovenkoA. A. SkrypnikPurpose – to analyze the structure of intracranial purulent-septic complications (IPSC), determine the factors influencing development of purulent-septic complications in patients with combat-related gunshot penetrating skull and brain wounds (CRPSBW), determine the effect of intracranial PSC on patients’ outcomes. A prospective analysis of results of examination and treatment of 121 patients was performed. All patients had gunshot penetrating skull and brain wounds sustained in combat conditions during a local armed conflict in the Eastern Ukraine. Evaluation of treatment outcome included analysis of mortality in 1 month (survived/died) and dichotomous Glasgow Outcome Scale (GOS) score in 12 months (favorable/unfavorable outcome). 121 wounded men aged 18 to 56 (average, 34.1±9.1) were included in the study. Intracranial purulent-septic complications (IPSC) were diagnosed in 14 (11.6%) gunshot CRPSBW patients. The following prognostic factors had statistically significantly correlation with the risk of intracranial purulent-septic complications development: wound liquorrhea on admission (p = 0.043), intraventricular hemorrhage (p = 0.007), bone fragments left in the wound (p = 0.0152), and duration of inflow-outflow wound drainage for more than 3 days (p= 0.0123). Intracranial PSC patients had mortality rate of 50%, and only 14.3% of those patients had a favorable outcome according to GOS score in one year. Presence of intracranial PSC had statistically significant association with mortality rate (p=0.0091) and GOS score in one year (p=0.0001).http://journals.uran.ua/index.php/2307-0404/article/view/181881purulent-septic complicationsintracranial complicationscraniocerebral woundscombat-related gunshot woundsprognostic factorsantibacterial therapymortalityoutcomes |
| spellingShingle | A. G. Sirko L. A. Dzyak G. S. Pylypenko I. O. Yovenko A. A. Skrypnik Prognostic factors of intracranial purulent-septic complications of combat-related gunshot penetrating skull and brain wounds. Medičnì Perspektivi purulent-septic complications intracranial complications craniocerebral wounds combat-related gunshot wounds prognostic factors antibacterial therapy mortality outcomes |
| title | Prognostic factors of intracranial purulent-septic complications of combat-related gunshot penetrating skull and brain wounds. |
| title_full | Prognostic factors of intracranial purulent-septic complications of combat-related gunshot penetrating skull and brain wounds. |
| title_fullStr | Prognostic factors of intracranial purulent-septic complications of combat-related gunshot penetrating skull and brain wounds. |
| title_full_unstemmed | Prognostic factors of intracranial purulent-septic complications of combat-related gunshot penetrating skull and brain wounds. |
| title_short | Prognostic factors of intracranial purulent-septic complications of combat-related gunshot penetrating skull and brain wounds. |
| title_sort | prognostic factors of intracranial purulent septic complications of combat related gunshot penetrating skull and brain wounds |
| topic | purulent-septic complications intracranial complications craniocerebral wounds combat-related gunshot wounds prognostic factors antibacterial therapy mortality outcomes |
| url | http://journals.uran.ua/index.php/2307-0404/article/view/181881 |
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