Pooled‐matrix protein interaction screens using Barcode Fusion Genetics

Pooled‐matrix protein interaction screens using Barcode Fusion Genetics

Abstract High‐throughput binary protein interaction mapping is continuing to extend our understanding of cellular function and disease mechanisms. However, we remain one or two orders of magnitude away from a complete interaction map for humans and other major model organisms. Completion will requir...

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Main Authors: Nozomu Yachie, Evangelia Petsalaki, Joseph C Mellor, Jochen Weile, Yves Jacob, Marta Verby, Sedide B Ozturk, Siyang Li, Atina G Cote, Roberto Mosca, Jennifer J Knapp, Minjeong Ko, Analyn Yu, Marinella Gebbia, Nidhi Sahni, Song Yi, Tanya Tyagi, Dayag Sheykhkarimli, Jonathan F Roth, Cassandra Wong, Louai Musa, Jamie Snider, Yi‐Chun Liu, Haiyuan Yu, Pascal Braun, Igor Stagljar, Tong Hao, Michael A Calderwood, Laurence Pelletier, Patrick Aloy, David E Hill, Marc Vidal, Frederick P Roth
Format: Article
Language:English
Published: Springer Nature 2016-04-01
Series:Molecular Systems Biology
Subjects:
DNA barcode
interactome
next‐generation sequencing
protein interaction
yeast two‐hybrid
Online Access:https://doi.org/10.15252/msb.20156660
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