Rehydration effect of qingshu buye decoction on exercise and high temperature-induced dehydration

Objective The aim of this study was to conduct a comprehensive evaluation of the rehydration efficacy of QSBYD and elucidate its potential underlying mechanism.Design 38 participants were randomly assigned to receive either QSBYD or placebo before and after exercise and heat-induced dehydration. Hyd...

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Main Authors: Huanyu Jiang, Jiankun Gao, Huan Wang, Lin Zhao, Yingduo Yang, Jiahua Ma, Shan Gu, Fenglin Hu, Quanyu Du, Fei Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Journal of the International Society of Sports Nutrition
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/15502783.2024.2393364
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author Huanyu Jiang
Jiankun Gao
Huan Wang
Lin Zhao
Yingduo Yang
Jiahua Ma
Shan Gu
Fenglin Hu
Quanyu Du
Fei Wang
author_facet Huanyu Jiang
Jiankun Gao
Huan Wang
Lin Zhao
Yingduo Yang
Jiahua Ma
Shan Gu
Fenglin Hu
Quanyu Du
Fei Wang
author_sort Huanyu Jiang
collection DOAJ
description Objective The aim of this study was to conduct a comprehensive evaluation of the rehydration efficacy of QSBYD and elucidate its potential underlying mechanism.Design 38 participants were randomly assigned to receive either QSBYD or placebo before and after exercise and heat-induced dehydration. Hydration indicators were measured over time. Blood tests assessed cellular anaerobic respiration metabolites, serum inflammatory markers, and coagulation markers. Perceptual measures of thirst, fatigue, and muscular soreness were also taken.Results QSBYD consumption resulted in lower urine volume (Control vs. QSBYD: 260.83 ± 167.99 ml vs. 187.78 ± 141.34 ml) and smaller decrease in percentage of nude body weight change from baseline (Control vs. QSBYD: −0.52 ± 0.89% vs. −0.07 ± 0.52%). Although no significant differences in urine specific gravity, QSBYD resulted in reduced urine volume at 120 min, suggesting improved fluid retention. Furthermore, QSBYD resulted in lower levels of IL-1β (Control vs. QSBYD: 2.40 ± 0.68 vs. 1.33 ± 0.66 pg/mL), suggesting QSBYD may provide benefits beyond hydration.Conclusion Further investigation into the underlying mechanisms and long-term effects of QSBYD on hydration is warranted. QSBYD may be an effective alternative to commercial sports drinks in mitigating dehydration effects.
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publishDate 2024-12-01
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series Journal of the International Society of Sports Nutrition
spelling doaj-art-0a0c55b896f444648ec69ce93c57a3c52024-12-12T06:10:57ZengTaylor & Francis GroupJournal of the International Society of Sports Nutrition1550-27832024-12-0121110.1080/15502783.2024.2393364Rehydration effect of qingshu buye decoction on exercise and high temperature-induced dehydrationHuanyu Jiang0Jiankun Gao1Huan Wang2Lin Zhao3Yingduo Yang4Jiahua Ma5Shan Gu6Fenglin Hu7Quanyu Du8Fei Wang9Chengdu University of Traditional Chinese Medicine, School of Basic Medical Sciences, Chengdu, ChinaSichuan College of Traditional Chinese Medicine, School of pharmacy, Mianyang, ChinaSichuan College of Traditional Chinese Medicine, Laboratory Training Center, Mianyang, ChinaSichuan College of Traditional Chinese Medicine, School of Traditional Chinese Medicine, Mianyang, ChinaUniversity of Southern California, Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, Los Angeles, USASichuan Depeiyuan Traditional Chinese Medicine Science & Technology Development Co., Ltd., Mianyang, ChinaSichuan Academy of Safety Science and Technology, Research and Development Department, Chengdu, ChinaSichuan Academy of Safety Science and Technology, Research and Development Department, Chengdu, ChinaHospital of Chengdu University of Traditional Chinese Medicine, Department of endocrinology, Chengdu, ChinaSichuan College of Traditional Chinese Medicine, School of Traditional Chinese Medicine, Mianyang, ChinaObjective The aim of this study was to conduct a comprehensive evaluation of the rehydration efficacy of QSBYD and elucidate its potential underlying mechanism.Design 38 participants were randomly assigned to receive either QSBYD or placebo before and after exercise and heat-induced dehydration. Hydration indicators were measured over time. Blood tests assessed cellular anaerobic respiration metabolites, serum inflammatory markers, and coagulation markers. Perceptual measures of thirst, fatigue, and muscular soreness were also taken.Results QSBYD consumption resulted in lower urine volume (Control vs. QSBYD: 260.83 ± 167.99 ml vs. 187.78 ± 141.34 ml) and smaller decrease in percentage of nude body weight change from baseline (Control vs. QSBYD: −0.52 ± 0.89% vs. −0.07 ± 0.52%). Although no significant differences in urine specific gravity, QSBYD resulted in reduced urine volume at 120 min, suggesting improved fluid retention. Furthermore, QSBYD resulted in lower levels of IL-1β (Control vs. QSBYD: 2.40 ± 0.68 vs. 1.33 ± 0.66 pg/mL), suggesting QSBYD may provide benefits beyond hydration.Conclusion Further investigation into the underlying mechanisms and long-term effects of QSBYD on hydration is warranted. QSBYD may be an effective alternative to commercial sports drinks in mitigating dehydration effects.https://www.tandfonline.com/doi/10.1080/15502783.2024.2393364Qingshu buye decoctionhydrationdehydrationexercisehigh temperature
spellingShingle Huanyu Jiang
Jiankun Gao
Huan Wang
Lin Zhao
Yingduo Yang
Jiahua Ma
Shan Gu
Fenglin Hu
Quanyu Du
Fei Wang
Rehydration effect of qingshu buye decoction on exercise and high temperature-induced dehydration
Journal of the International Society of Sports Nutrition
Qingshu buye decoction
hydration
dehydration
exercise
high temperature
title Rehydration effect of qingshu buye decoction on exercise and high temperature-induced dehydration
title_full Rehydration effect of qingshu buye decoction on exercise and high temperature-induced dehydration
title_fullStr Rehydration effect of qingshu buye decoction on exercise and high temperature-induced dehydration
title_full_unstemmed Rehydration effect of qingshu buye decoction on exercise and high temperature-induced dehydration
title_short Rehydration effect of qingshu buye decoction on exercise and high temperature-induced dehydration
title_sort rehydration effect of qingshu buye decoction on exercise and high temperature induced dehydration
topic Qingshu buye decoction
hydration
dehydration
exercise
high temperature
url https://www.tandfonline.com/doi/10.1080/15502783.2024.2393364
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