Metabolic rewiring in keratinocytes by miR‐31‐5p identifies therapeutic intervention for psoriasis

Metabolic rewiring in keratinocytes by miR‐31‐5p identifies therapeutic intervention for psoriasis

Abstract Besides genetic alterations, the cellular environment also determines disease onset and progression. When different cell types contribute to disease outcome, this imposes environmental challenges as different cell types likely differ in their extracellular dependencies. Hsa‐microRNA‐31‐5p (...

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Main Authors: Mao‐Jie Wang, Huan‐Jie Huang, Yong‐Yue Xu, Harmjan Vos, Can Gulersonmez, Edwin Stigter, Johan Gerritsen, Marc Pages Gallego, Robert van Es, Li Li, Hao Deng, Lin Han, Run‐Yue Huang, Chuan‐Jian Lu, Boudewijn MT Burgering
Format: Article
Language:English
Published: Springer Nature 2023-03-01
Series:EMBO Molecular Medicine
Subjects:
glutaminolysis
metabolism reprogramming
miR‐31
psoriasis
T helper 17 cells
Online Access:https://doi.org/10.15252/emmm.202215674
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https://doi.org/10.15252/emmm.202215674

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