Quantifying intratumoral heterogeneity within sub-regions to predict high-grade patterns in clinical stage I solid lung adenocarcinoma

Quantifying intratumoral heterogeneity within sub-regions to predict high-grade patterns in clinical stage I solid lung adenocarcinoma

Abstract Background This study aims to quantify intratumoral heterogeneity (ITH) using preoperative CT image and evaluate its ability to predict pathological high-grade patterns, specifically micropapillary and/or solid components (MP/S), in patients diagnosed with clinical stage I solid lung adenoc...

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Bibliographic Details
Main Authors: Zhichao Zuo, Jinqiu Deng, Wu Ge, Yinjun Zhou, Haibo Liu, Wei Zhang, Ying Zeng
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Cancer
Subjects:
Intratumoral heterogeneity
Sub-regions
High-grade patterns
Clinical stage I
Solid lung adenocarcinoma
Online Access:https://doi.org/10.1186/s12885-025-13445-0
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