Types of Injuries and the Severity of Shoulder Dysfunction Associated with Diabetes Mellitus in Patients with Functional Impairment: A Case–Control Study

Background/Objectives: Patients with diabetes have been reported to experience a higher prevalence of shoulder disorders compared to those without diabetes or with other medical conditions. However, the specific types of shoulder injuries and the extent of functional impairment associated with diabe...

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Main Authors: Mercedes Fuentes-Murguia, Karla B. Carrazco-Peña, Osiris G. Delgado-Enciso, Joel Castellanos-Gomez, Gustavo A. Hernandez-Fuentes, Fabian Rojas-Larios, Carmen A. Sanchez-Ramirez, Margarita L. Martinez-Fierro, Iram P. Rodriguez-Sanchez, José Guzmán-Esquivel, Idalia Garza-Veloz, José E. Del-Río-Valdivia, Jorge E. Plata-Florenzano, Iván Delgado-Enciso
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biomedicines
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Online Access:https://www.mdpi.com/2227-9059/12/11/2634
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author Mercedes Fuentes-Murguia
Karla B. Carrazco-Peña
Osiris G. Delgado-Enciso
Joel Castellanos-Gomez
Gustavo A. Hernandez-Fuentes
Fabian Rojas-Larios
Carmen A. Sanchez-Ramirez
Margarita L. Martinez-Fierro
Iram P. Rodriguez-Sanchez
José Guzmán-Esquivel
Idalia Garza-Veloz
José E. Del-Río-Valdivia
Jorge E. Plata-Florenzano
Iván Delgado-Enciso
author_facet Mercedes Fuentes-Murguia
Karla B. Carrazco-Peña
Osiris G. Delgado-Enciso
Joel Castellanos-Gomez
Gustavo A. Hernandez-Fuentes
Fabian Rojas-Larios
Carmen A. Sanchez-Ramirez
Margarita L. Martinez-Fierro
Iram P. Rodriguez-Sanchez
José Guzmán-Esquivel
Idalia Garza-Veloz
José E. Del-Río-Valdivia
Jorge E. Plata-Florenzano
Iván Delgado-Enciso
author_sort Mercedes Fuentes-Murguia
collection DOAJ
description Background/Objectives: Patients with diabetes have been reported to experience a higher prevalence of shoulder disorders compared to those without diabetes or with other medical conditions. However, the specific types of shoulder injuries and the extent of functional impairment associated with diabetes mellitus remain unclear. This study aimed to assess the association between diabetes and specific shoulder injuries, as well as the degree of functional impairment in affected patients. Methods: A case–control study was conducted involving 136 patients with shoulder functional impairment (UCLA Shoulder Scale ≤ 27). The study included 38 patients with diabetes and 98 non-diabetic controls. Shoulder injuries were diagnosed using ultrasonography, focusing on the supraspinatus tendon, long head of the biceps tendon, subscapularis tendon, and the presence of adhesive capsulitis or rotator cuff tears. Results: Diabetic patients had significantly higher rates of poor shoulder function compared to non-diabetic controls (89.47% vs. 63.26%, adjusted OR [adOR] 5.22, 95% CI 1.57–17.32, <i>p</i> = 0.007). While both groups had high rates of supraspinatus and long head of the biceps tendon injuries (~80%), no significant differences were found between them (<i>p</i> > 0.300). However, diabetic patients were more than three times as likely to have subscapularis tendon injuries (adOR 3.15, 95% CI 1.26–7.90, <i>p</i> = 0.014) and massive rotator cuff tears (adOR 3.76, 95% CI 1.16–12.15, <i>p</i> = 0.027). Additionally, diabetes was associated with a fourfold increased risk of adhesive capsulitis (adOR 4.16, 95% CI 1.20–14.47, <i>p</i> = 0.025). Conclusions: Diabetes mellitus is linked to greater functional and structural deterioration of the shoulder, highlighting the importance of considering diabetes as a risk factor for specific shoulder injuries. Early diagnosis and treatment may improve outcomes for diabetic patients with shoulder disorders.
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spelling doaj-art-09b8cc1bcb0d497e843a7a0ef54c8f442024-11-26T17:53:30ZengMDPI AGBiomedicines2227-90592024-11-011211263410.3390/biomedicines12112634Types of Injuries and the Severity of Shoulder Dysfunction Associated with Diabetes Mellitus in Patients with Functional Impairment: A Case–Control StudyMercedes Fuentes-Murguia0Karla B. Carrazco-Peña1Osiris G. Delgado-Enciso2Joel Castellanos-Gomez3Gustavo A. Hernandez-Fuentes4Fabian Rojas-Larios5Carmen A. Sanchez-Ramirez6Margarita L. Martinez-Fierro7Iram P. Rodriguez-Sanchez8José Guzmán-Esquivel9Idalia Garza-Veloz10José E. Del-Río-Valdivia11Jorge E. Plata-Florenzano12Iván Delgado-Enciso13School of Medicine, University of Colima, Colima 28040, MexicoSchool of Medicine, University of Colima, Colima 28040, MexicoSchool of Medicine, University of Colima, Colima 28040, MexicoInstitute for Social Security and Services for State Workers (ISSSTE), State Delegation of Colima, Colima 28017, MexicoSchool of Medicine, University of Colima, Colima 28040, MexicoSchool of Medicine, University of Colima, Colima 28040, MexicoSchool of Medicine, University of Colima, Colima 28040, MexicoMolecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas 98160, MexicoMolecular and Structural Physiology Laboratory, School of Biological Sciences, Autonomous University of Nuevo Leon, San Nicolas de los Garza 66455, MexicoClinical Epidemiology Research Unit, Mexican Institute of Social Security (IMSS), Villa de Alvarez, Colima 29883, MexicoMolecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas 98160, MexicoSchool of Medicine, University of Colima, Colima 28040, MexicoCancerology State Institute, Colima State Health Services, Colima 28085, MexicoSchool of Medicine, University of Colima, Colima 28040, MexicoBackground/Objectives: Patients with diabetes have been reported to experience a higher prevalence of shoulder disorders compared to those without diabetes or with other medical conditions. However, the specific types of shoulder injuries and the extent of functional impairment associated with diabetes mellitus remain unclear. This study aimed to assess the association between diabetes and specific shoulder injuries, as well as the degree of functional impairment in affected patients. Methods: A case–control study was conducted involving 136 patients with shoulder functional impairment (UCLA Shoulder Scale ≤ 27). The study included 38 patients with diabetes and 98 non-diabetic controls. Shoulder injuries were diagnosed using ultrasonography, focusing on the supraspinatus tendon, long head of the biceps tendon, subscapularis tendon, and the presence of adhesive capsulitis or rotator cuff tears. Results: Diabetic patients had significantly higher rates of poor shoulder function compared to non-diabetic controls (89.47% vs. 63.26%, adjusted OR [adOR] 5.22, 95% CI 1.57–17.32, <i>p</i> = 0.007). While both groups had high rates of supraspinatus and long head of the biceps tendon injuries (~80%), no significant differences were found between them (<i>p</i> > 0.300). However, diabetic patients were more than three times as likely to have subscapularis tendon injuries (adOR 3.15, 95% CI 1.26–7.90, <i>p</i> = 0.014) and massive rotator cuff tears (adOR 3.76, 95% CI 1.16–12.15, <i>p</i> = 0.027). Additionally, diabetes was associated with a fourfold increased risk of adhesive capsulitis (adOR 4.16, 95% CI 1.20–14.47, <i>p</i> = 0.025). Conclusions: Diabetes mellitus is linked to greater functional and structural deterioration of the shoulder, highlighting the importance of considering diabetes as a risk factor for specific shoulder injuries. Early diagnosis and treatment may improve outcomes for diabetic patients with shoulder disorders.https://www.mdpi.com/2227-9059/12/11/2634diabetes mellitusfunctional impairment of the shoulderrotator cuff tendonadhesive capsulitisultrasonographycase–control study
spellingShingle Mercedes Fuentes-Murguia
Karla B. Carrazco-Peña
Osiris G. Delgado-Enciso
Joel Castellanos-Gomez
Gustavo A. Hernandez-Fuentes
Fabian Rojas-Larios
Carmen A. Sanchez-Ramirez
Margarita L. Martinez-Fierro
Iram P. Rodriguez-Sanchez
José Guzmán-Esquivel
Idalia Garza-Veloz
José E. Del-Río-Valdivia
Jorge E. Plata-Florenzano
Iván Delgado-Enciso
Types of Injuries and the Severity of Shoulder Dysfunction Associated with Diabetes Mellitus in Patients with Functional Impairment: A Case–Control Study
Biomedicines
diabetes mellitus
functional impairment of the shoulder
rotator cuff tendon
adhesive capsulitis
ultrasonography
case–control study
title Types of Injuries and the Severity of Shoulder Dysfunction Associated with Diabetes Mellitus in Patients with Functional Impairment: A Case–Control Study
title_full Types of Injuries and the Severity of Shoulder Dysfunction Associated with Diabetes Mellitus in Patients with Functional Impairment: A Case–Control Study
title_fullStr Types of Injuries and the Severity of Shoulder Dysfunction Associated with Diabetes Mellitus in Patients with Functional Impairment: A Case–Control Study
title_full_unstemmed Types of Injuries and the Severity of Shoulder Dysfunction Associated with Diabetes Mellitus in Patients with Functional Impairment: A Case–Control Study
title_short Types of Injuries and the Severity of Shoulder Dysfunction Associated with Diabetes Mellitus in Patients with Functional Impairment: A Case–Control Study
title_sort types of injuries and the severity of shoulder dysfunction associated with diabetes mellitus in patients with functional impairment a case control study
topic diabetes mellitus
functional impairment of the shoulder
rotator cuff tendon
adhesive capsulitis
ultrasonography
case–control study
url https://www.mdpi.com/2227-9059/12/11/2634
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