Tumor microenvironment-responsive engineered hybrid nanomedicine for photodynamic-immunotherapy via multi-pronged amplification of reactive oxygen species
Abstract Reactive oxygen species (ROS) is promising in cancer therapy by accelerating tumor cell death, whose therapeutic efficacy, however, is greatly limited by the hypoxia in the tumor microenvironment (TME) and the antioxidant defense. Amplification of oxidative stress has been successfully empl...
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Main Authors: | Jinglin Zou, Cong Jiang, Qiangsheng Hu, Xinlin Jia, Shuqi Wang, Shiyue Wan, Yuanqing Mao, Dapeng Zhang, Peng Zhang, Bin Dai, Yongsheng Li |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-55658-0 |
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