Transcription of a centromere-enriched retroelement and local retention of its RNA are significant features of the CENP-A chromatin landscape

Transcription of a centromere-enriched retroelement and local retention of its RNA are significant features of the CENP-A chromatin landscape

Abstract Background Centromeres depend on chromatin containing the conserved histone H3 variant CENP-A for function and inheritance, while the role of centromeric DNA repeats remains unclear. Retroelements are prevalent at centromeres across taxa and represent a potential mechanism for promoting tra...

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Main Authors: B. J. Chabot, R. Sun, A. Amjad, S. J. Hoyt, L. Ouyang, C. Courret, R. Drennan, L. Leo, A. M. Larracuente, L. J. Core, R. J. O’Neill, B. G. Mellone
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-024-03433-1
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