Enhanced biosynthesis of poly(3‐hydroxybutyrate) in engineered strains of Pseudomonas putida via increased malonyl‐CoA availability

Abstract Malonyl‐coenzyme A (CoA) is a key precursor for the biosynthesis of multiple value‐added compounds by microbial cell factories, including polyketides, carboxylic acids, biofuels, and polyhydroxyalkanoates. Owing to its role as a metabolic hub, malonyl‐CoA availability is limited by competit...

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Bibliographic Details
Main Authors: Giusi Favoino, Nicolas Krink, Tobias Schwanemann, Nick Wierckx, Pablo I. Nikel
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Microbial Biotechnology
Online Access:https://doi.org/10.1111/1751-7915.70044
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