Cell-based therapies reverse the heart failure-altered right ventricular proteome towards a pre-disease state

Cell-based therapies reverse the heart failure-altered right ventricular proteome towards a pre-disease state

Abstract Background Congenital heart defects can lead to right ventricular (RV) pressure-overload and heart failure. Cell-based therapies, including mesenchymal stromal cells (MSCs) and c-kit positive cells (CPCs) have been studied clinically as options to restore heart function in disease states. M...

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Bibliographic Details
Main Authors: Nour Makkaoui, Vidhya Prasad, Pritha Bagchi, Tiffany Carmona, Ke Li, Olivia L. Latham, Yuanyuan Zhang, Jingyun Lee, Cristina M. Furdui, Joshua T. Maxwell
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Stem Cell Research & Therapy
Subjects:
Proteomics
Stem cells
Heart failure
Online Access:https://doi.org/10.1186/s13287-024-04009-3
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