A Challenging Case of Miliary Tuberculosis in Pregnancy

Miliary tuberculosis (TB) is an uncommon yet severe condition that can pose substantial risks to pregnant women and their unborn child. This case study describes a 22-year-old pregnant female at 23 weeks of gestation presented with breathlessness, fever accompanied by chills, dry cough, and loss of...

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Main Authors: Anuja Singh, Farha Siddiqui, Anand Kumar Maurya, Shashank Purwar, Saurabh Saigal
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:International Journal of Mycobacteriology
Subjects:
Online Access:https://journals.lww.com/10.4103/ijmy.ijmy_216_24
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author Anuja Singh
Farha Siddiqui
Anand Kumar Maurya
Shashank Purwar
Saurabh Saigal
author_facet Anuja Singh
Farha Siddiqui
Anand Kumar Maurya
Shashank Purwar
Saurabh Saigal
author_sort Anuja Singh
collection DOAJ
description Miliary tuberculosis (TB) is an uncommon yet severe condition that can pose substantial risks to pregnant women and their unborn child. This case study describes a 22-year-old pregnant female at 23 weeks of gestation presented with breathlessness, fever accompanied by chills, dry cough, and loss of appetite. With no significant comorbidities, her initial symptoms were inconclusive, leading to her initial diagnosis as a case of pyrexia of unknown origin. Despite receiving iron supplements for anemia and broad-spectrum antibiotics, her health continued to decline, prompting her transfer to a specialized medical center where advanced molecular testing ultimately confirmed a diagnosis of miliary TB. Upon admission, she was promptly started on anti-TB therapy and managed in the intensive care unit, where her clinical course included the development of acute respiratory distress syndrome (ARDS) requiring ventilatory support. Through meticulous monitoring and multidisciplinary intervention, the patient stabilized and ultimately delivered a healthy baby girl through normal vaginal delivery. Miliary TB, though rare, is challenging to diagnose during pregnancy due to overlapping symptoms with other conditions. This case underscores the critical importance of recognizing the atypical presentations of miliary TB in pregnant women, particularly in the context of previous exposure. It highlights the need for high clinical suspicion, timely diagnosis, and comprehensive management strategies to ensure favorable outcomes for both mother and child in the face of such challenging clinical scenarios.
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publishDate 2024-12-01
publisher Wolters Kluwer Medknow Publications
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series International Journal of Mycobacteriology
spelling doaj-art-095ce30687984e8594cffbaa6c9599862025-01-07T06:19:07ZengWolters Kluwer Medknow PublicationsInternational Journal of Mycobacteriology2212-55312212-554X2024-12-0113444845110.4103/ijmy.ijmy_216_24A Challenging Case of Miliary Tuberculosis in PregnancyAnuja SinghFarha SiddiquiAnand Kumar MauryaShashank PurwarSaurabh SaigalMiliary tuberculosis (TB) is an uncommon yet severe condition that can pose substantial risks to pregnant women and their unborn child. This case study describes a 22-year-old pregnant female at 23 weeks of gestation presented with breathlessness, fever accompanied by chills, dry cough, and loss of appetite. With no significant comorbidities, her initial symptoms were inconclusive, leading to her initial diagnosis as a case of pyrexia of unknown origin. Despite receiving iron supplements for anemia and broad-spectrum antibiotics, her health continued to decline, prompting her transfer to a specialized medical center where advanced molecular testing ultimately confirmed a diagnosis of miliary TB. Upon admission, she was promptly started on anti-TB therapy and managed in the intensive care unit, where her clinical course included the development of acute respiratory distress syndrome (ARDS) requiring ventilatory support. Through meticulous monitoring and multidisciplinary intervention, the patient stabilized and ultimately delivered a healthy baby girl through normal vaginal delivery. Miliary TB, though rare, is challenging to diagnose during pregnancy due to overlapping symptoms with other conditions. This case underscores the critical importance of recognizing the atypical presentations of miliary TB in pregnant women, particularly in the context of previous exposure. It highlights the need for high clinical suspicion, timely diagnosis, and comprehensive management strategies to ensure favorable outcomes for both mother and child in the face of such challenging clinical scenarios.https://journals.lww.com/10.4103/ijmy.ijmy_216_24gene-xpertline probe assaymiliary tuberculosispregnancy
spellingShingle Anuja Singh
Farha Siddiqui
Anand Kumar Maurya
Shashank Purwar
Saurabh Saigal
A Challenging Case of Miliary Tuberculosis in Pregnancy
International Journal of Mycobacteriology
gene-xpert
line probe assay
miliary tuberculosis
pregnancy
title A Challenging Case of Miliary Tuberculosis in Pregnancy
title_full A Challenging Case of Miliary Tuberculosis in Pregnancy
title_fullStr A Challenging Case of Miliary Tuberculosis in Pregnancy
title_full_unstemmed A Challenging Case of Miliary Tuberculosis in Pregnancy
title_short A Challenging Case of Miliary Tuberculosis in Pregnancy
title_sort challenging case of miliary tuberculosis in pregnancy
topic gene-xpert
line probe assay
miliary tuberculosis
pregnancy
url https://journals.lww.com/10.4103/ijmy.ijmy_216_24
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