LungVis 1.0: an automatic AI-powered 3D imaging ecosystem unveils spatial profiling of nanoparticle delivery and acinar migration of lung macrophages

LungVis 1.0: an automatic AI-powered 3D imaging ecosystem unveils spatial profiling of nanoparticle delivery and acinar migration of lung macrophages

Abstract Targeted (nano-)drug delivery is essential for treating respiratory diseases, which are often confined to distinct lung regions. However, spatio-temporal profiling of drugs or nanoparticles (NPs) and their interactions with lung macrophages remains unresolved. Here, we present LungVis 1.0,...

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Main Authors: Lin Yang, Qiongliang Liu, Pramod Kumar, Arunima Sengupta, Ali Farnoud, Ruolin Shen, Darya Trofimova, Sebastian Ziegler, Neda Davoudi, Ali Doryab, Ali Önder Yildirim, Markus E. Diefenbacher, Herbert B. Schiller, Daniel Razansky, Marie Piraud, Gerald Burgstaller, Wolfgang G. Kreyling, Fabian Isensee, Markus Rehberg, Tobias Stoeger, Otmar Schmid
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54267-1
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https://doi.org/10.1038/s41467-024-54267-1

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