Juvenile Xanthogranuloma: A Case Report and Literature Review of an Underdiagnosed Benign Entity

Juvenile xanthogranuloma (JXG) is an uncommon non-Langerhans cell histiocytic lesion that usually occurs at an early age and is asymptomatic. It is usually a self-limiting disorder, and predilection sites are the head and neck, extremities, and trunk. We report a 3-year-old male child who presented...

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Main Authors: Paruvathavarthini Thambiraj, Kalaivanan Balasubramanian, Bheemanathi Hanuman Srinivas
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:International Journal of Advanced Medical and Health Research
Subjects:
Online Access:https://journals.lww.com/10.4103/ijamr.ijamr_158_24
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author Paruvathavarthini Thambiraj
Kalaivanan Balasubramanian
Bheemanathi Hanuman Srinivas
author_facet Paruvathavarthini Thambiraj
Kalaivanan Balasubramanian
Bheemanathi Hanuman Srinivas
author_sort Paruvathavarthini Thambiraj
collection DOAJ
description Juvenile xanthogranuloma (JXG) is an uncommon non-Langerhans cell histiocytic lesion that usually occurs at an early age and is asymptomatic. It is usually a self-limiting disorder, and predilection sites are the head and neck, extremities, and trunk. We report a 3-year-old male child who presented to the hospital with asymptomatic swelling in the right upper eyelid region. Excision biopsy was done, and histopathology along with immunohistochemistry was reported as JXG. It is essential to differentiate this condition from childhood malignancy.
format Article
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institution Kabale University
issn 2349-4220
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language English
publishDate 2024-12-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series International Journal of Advanced Medical and Health Research
spelling doaj-art-09006ba357064a568b4babec7342f1442025-01-08T13:21:44ZengWolters Kluwer Medknow PublicationsInternational Journal of Advanced Medical and Health Research2349-42202350-02982024-12-0111212913110.4103/ijamr.ijamr_158_24Juvenile Xanthogranuloma: A Case Report and Literature Review of an Underdiagnosed Benign EntityParuvathavarthini ThambirajKalaivanan BalasubramanianBheemanathi Hanuman SrinivasJuvenile xanthogranuloma (JXG) is an uncommon non-Langerhans cell histiocytic lesion that usually occurs at an early age and is asymptomatic. It is usually a self-limiting disorder, and predilection sites are the head and neck, extremities, and trunk. We report a 3-year-old male child who presented to the hospital with asymptomatic swelling in the right upper eyelid region. Excision biopsy was done, and histopathology along with immunohistochemistry was reported as JXG. It is essential to differentiate this condition from childhood malignancy.https://journals.lww.com/10.4103/ijamr.ijamr_158_24case reportschildhood malignancyjuvenile xanthogranulomalangerhans cell histiocytosisxanthogranulomas
spellingShingle Paruvathavarthini Thambiraj
Kalaivanan Balasubramanian
Bheemanathi Hanuman Srinivas
Juvenile Xanthogranuloma: A Case Report and Literature Review of an Underdiagnosed Benign Entity
International Journal of Advanced Medical and Health Research
case reports
childhood malignancy
juvenile xanthogranuloma
langerhans cell histiocytosis
xanthogranulomas
title Juvenile Xanthogranuloma: A Case Report and Literature Review of an Underdiagnosed Benign Entity
title_full Juvenile Xanthogranuloma: A Case Report and Literature Review of an Underdiagnosed Benign Entity
title_fullStr Juvenile Xanthogranuloma: A Case Report and Literature Review of an Underdiagnosed Benign Entity
title_full_unstemmed Juvenile Xanthogranuloma: A Case Report and Literature Review of an Underdiagnosed Benign Entity
title_short Juvenile Xanthogranuloma: A Case Report and Literature Review of an Underdiagnosed Benign Entity
title_sort juvenile xanthogranuloma a case report and literature review of an underdiagnosed benign entity
topic case reports
childhood malignancy
juvenile xanthogranuloma
langerhans cell histiocytosis
xanthogranulomas
url https://journals.lww.com/10.4103/ijamr.ijamr_158_24
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AT kalaivananbalasubramanian juvenilexanthogranulomaacasereportandliteraturereviewofanunderdiagnosedbenignentity
AT bheemanathihanumansrinivas juvenilexanthogranulomaacasereportandliteraturereviewofanunderdiagnosedbenignentity