The Production of Nickel-Chromium-Molybdenum Alloy with Open Pore Structure as an Implant and the Investigation of Its Biocompatibility In Vivo

A dental crown material, Nickel-Chrome-Molybdenum alloy, is manufactured using precision casting method from a polyurethane foam model in a regular and open-pore form, as a hard tissue implant for orthopedic applications. The samples produced have 10, 20, and 30 (±3) pores per inch of pore densities...

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Main Authors: Yusuf Er, Emine Unsaldi
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Advances in Materials Science and Engineering
Online Access:http://dx.doi.org/10.1155/2013/568479
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author Yusuf Er
Emine Unsaldi
author_facet Yusuf Er
Emine Unsaldi
author_sort Yusuf Er
collection DOAJ
description A dental crown material, Nickel-Chrome-Molybdenum alloy, is manufactured using precision casting method from a polyurethane foam model in a regular and open-pore form, as a hard tissue implant for orthopedic applications. The samples produced have 10, 20, and 30 (±3) pores per inch of pore densities and 0.0008, 0.0017, and 0.0027 g/mm3 densities, respectively. Samples were implanted in six dogs and observed for a period of two, four, and six months for the histopathological examinations. The dogs were examined radiologically in 15-day intervals and clinically in certain intervals. The implants were taken out with surrounding tissue at the end of these periods. Implants and surrounding tissues were examined histopathologically in terms of biocompatibility. As a result, it is seen that new bone tissue was formed, in pores of the porous implant at the head of the tibia in dogs implanted. Any pathology, inflammation, and reaction in old and new tissues were not observed. It was concluded that a dental alloy (Ni-Cr-Mo alloy) could also be used as a biocompatible hard tissue implant material for orthopedics.
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spelling doaj-art-08e6bde4819a40b4b88c47b3a03f53862025-08-20T03:55:33ZengWileyAdvances in Materials Science and Engineering1687-84341687-84422013-01-01201310.1155/2013/568479568479The Production of Nickel-Chromium-Molybdenum Alloy with Open Pore Structure as an Implant and the Investigation of Its Biocompatibility In VivoYusuf Er0Emine Unsaldi1Department of Metallurgy Education, Gazi Vocational High School, Directorate of National Education, 23100 Elazig, TurkeyDepartment of Surgery, Faculty of Veterinary, Firat University, 23119 Elazig, TurkeyA dental crown material, Nickel-Chrome-Molybdenum alloy, is manufactured using precision casting method from a polyurethane foam model in a regular and open-pore form, as a hard tissue implant for orthopedic applications. The samples produced have 10, 20, and 30 (±3) pores per inch of pore densities and 0.0008, 0.0017, and 0.0027 g/mm3 densities, respectively. Samples were implanted in six dogs and observed for a period of two, four, and six months for the histopathological examinations. The dogs were examined radiologically in 15-day intervals and clinically in certain intervals. The implants were taken out with surrounding tissue at the end of these periods. Implants and surrounding tissues were examined histopathologically in terms of biocompatibility. As a result, it is seen that new bone tissue was formed, in pores of the porous implant at the head of the tibia in dogs implanted. Any pathology, inflammation, and reaction in old and new tissues were not observed. It was concluded that a dental alloy (Ni-Cr-Mo alloy) could also be used as a biocompatible hard tissue implant material for orthopedics.http://dx.doi.org/10.1155/2013/568479
spellingShingle Yusuf Er
Emine Unsaldi
The Production of Nickel-Chromium-Molybdenum Alloy with Open Pore Structure as an Implant and the Investigation of Its Biocompatibility In Vivo
Advances in Materials Science and Engineering
title The Production of Nickel-Chromium-Molybdenum Alloy with Open Pore Structure as an Implant and the Investigation of Its Biocompatibility In Vivo
title_full The Production of Nickel-Chromium-Molybdenum Alloy with Open Pore Structure as an Implant and the Investigation of Its Biocompatibility In Vivo
title_fullStr The Production of Nickel-Chromium-Molybdenum Alloy with Open Pore Structure as an Implant and the Investigation of Its Biocompatibility In Vivo
title_full_unstemmed The Production of Nickel-Chromium-Molybdenum Alloy with Open Pore Structure as an Implant and the Investigation of Its Biocompatibility In Vivo
title_short The Production of Nickel-Chromium-Molybdenum Alloy with Open Pore Structure as an Implant and the Investigation of Its Biocompatibility In Vivo
title_sort production of nickel chromium molybdenum alloy with open pore structure as an implant and the investigation of its biocompatibility in vivo
url http://dx.doi.org/10.1155/2013/568479
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