Three‐dimensional morphological revealing of human placental villi with common obstetric complications via optical coherence tomography
Abstract Placental villi play a vital role in human fetal development, acting as the bridge of material exchange between the maternal and fetal. The abnormal morphology of placental villi is closely related to placental circulation disorder and pregnancy complications. Revealing placental villi thre...
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | Bioengineering & Translational Medicine |
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| Online Access: | https://doi.org/10.1002/btm2.10372 |
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| author | Guangming Ni Junming Zhong Xuemei Gao Renxiong Wu Wenjing Wang Xiaoshan Wang Yao Xie Yong Liu Jie Mei |
| author_facet | Guangming Ni Junming Zhong Xuemei Gao Renxiong Wu Wenjing Wang Xiaoshan Wang Yao Xie Yong Liu Jie Mei |
| author_sort | Guangming Ni |
| collection | DOAJ |
| description | Abstract Placental villi play a vital role in human fetal development, acting as the bridge of material exchange between the maternal and fetal. The abnormal morphology of placental villi is closely related to placental circulation disorder and pregnancy complications. Revealing placental villi three‐dimensional (3D) morphology of common obstetric complications and healthy pregnancies provides a new perspective for studying the role of the placenta and its villi in the development of pregnancy diseases. In this study, we established a noninvasive, high‐resolution 3D imaging platform via optical coherence tomography to reveal placental villi 3D morphological information of diseased and normal placentae. For the first time, 3D morphologies of placental villous tree structures in common obstetric complications were quantitatively revealed and corresponding 3D information could visualize the morphological characteristics of the placental villous tree from a more intuitive perspective, providing helpful information to the study of fetal development, feto‐maternal material exchange, and gestational complications treatment. |
| format | Article |
| id | doaj-art-08e2cc2f3ced45549c4dc687b177330b |
| institution | Kabale University |
| issn | 2380-6761 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Bioengineering & Translational Medicine |
| spelling | doaj-art-08e2cc2f3ced45549c4dc687b177330b2024-11-21T05:16:03ZengWileyBioengineering & Translational Medicine2380-67612023-01-0181n/an/a10.1002/btm2.10372Three‐dimensional morphological revealing of human placental villi with common obstetric complications via optical coherence tomographyGuangming Ni0Junming Zhong1Xuemei Gao2Renxiong Wu3Wenjing Wang4Xiaoshan Wang5Yao Xie6Yong Liu7Jie Mei8School of Optoelectronic Science and Engineering University of Electronic Science and Technology of China Chengdu ChinaSchool of Optoelectronic Science and Engineering University of Electronic Science and Technology of China Chengdu ChinaDepartment of Obstetrics and Gynaecology Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China Chengdu Sichuan ChinaSchool of Optoelectronic Science and Engineering University of Electronic Science and Technology of China Chengdu ChinaDepartment of Obstetrics and Gynaecology Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China Chengdu Sichuan ChinaCancer Center of University of Electronic Science and Technology of China and Sichuan Provincial People's Hospital Chengdu ChinaDepartment of Obstetrics and Gynaecology Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China Chengdu Sichuan ChinaSchool of Optoelectronic Science and Engineering University of Electronic Science and Technology of China Chengdu ChinaDepartment of Obstetrics and Gynaecology Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China Chengdu Sichuan ChinaAbstract Placental villi play a vital role in human fetal development, acting as the bridge of material exchange between the maternal and fetal. The abnormal morphology of placental villi is closely related to placental circulation disorder and pregnancy complications. Revealing placental villi three‐dimensional (3D) morphology of common obstetric complications and healthy pregnancies provides a new perspective for studying the role of the placenta and its villi in the development of pregnancy diseases. In this study, we established a noninvasive, high‐resolution 3D imaging platform via optical coherence tomography to reveal placental villi 3D morphological information of diseased and normal placentae. For the first time, 3D morphologies of placental villous tree structures in common obstetric complications were quantitatively revealed and corresponding 3D information could visualize the morphological characteristics of the placental villous tree from a more intuitive perspective, providing helpful information to the study of fetal development, feto‐maternal material exchange, and gestational complications treatment.https://doi.org/10.1002/btm2.10372common obstetric complicationsoptical coherence tomographyplacental villithree‐dimensional morphology |
| spellingShingle | Guangming Ni Junming Zhong Xuemei Gao Renxiong Wu Wenjing Wang Xiaoshan Wang Yao Xie Yong Liu Jie Mei Three‐dimensional morphological revealing of human placental villi with common obstetric complications via optical coherence tomography Bioengineering & Translational Medicine common obstetric complications optical coherence tomography placental villi three‐dimensional morphology |
| title | Three‐dimensional morphological revealing of human placental villi with common obstetric complications via optical coherence tomography |
| title_full | Three‐dimensional morphological revealing of human placental villi with common obstetric complications via optical coherence tomography |
| title_fullStr | Three‐dimensional morphological revealing of human placental villi with common obstetric complications via optical coherence tomography |
| title_full_unstemmed | Three‐dimensional morphological revealing of human placental villi with common obstetric complications via optical coherence tomography |
| title_short | Three‐dimensional morphological revealing of human placental villi with common obstetric complications via optical coherence tomography |
| title_sort | three dimensional morphological revealing of human placental villi with common obstetric complications via optical coherence tomography |
| topic | common obstetric complications optical coherence tomography placental villi three‐dimensional morphology |
| url | https://doi.org/10.1002/btm2.10372 |
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