Impact of vancomycin therapeutic drug monitoring on mortality in sepsis patients across different age groups: a propensity score-matched retrospective cohort study

Impact of vancomycin therapeutic drug monitoring on mortality in sepsis patients across different age groups: a propensity score-matched retrospective cohort study

BackgroundDue to its potent antibacterial activity, vancomycin is widely used in the treatment of sepsis. Therapeutic drug monitoring (TDM) can optimize personalized vancomycin dosing regimens, enhancing therapeutic efficacy and minimizing nephrotoxic risk, thereby potentially improving patient outc...

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Bibliographic Details
Main Authors: Huaidong Peng, Ruichang Zhang, Shuangwu Zhou, Tingting Xu, Ruolun Wang, Qilin Yang, Xunlong Zhong, Xiaorui Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Medicine
Subjects:
vancomycin
therapeutic drug monitoring
sepsis
mortality
age
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1498337/full
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