The association between underlying conditions, risk factors, risk markers, and post-COVID conditions ≥6 months after COVID-19: A systematic review
Introduction: While various demographic factors and underlying medical conditions are associated with the development of post-COVID conditions within a month after SARS-CoV-2 infection, less is known about factors associated with post-COVID symptoms that persist for 6 months or more. The aim of this...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2024-12-01
|
| Series: | Journal of Family Medicine and Primary Care |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jfmpc.jfmpc_247_24 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841545796763254784 |
|---|---|
| author | Aisha Hill Madelon Morford Sharon Saydah Pamela Logan Danielle Raso Erin C. Stone Joanna Taliano Emilia H. Koumans Olga Varechtchouk |
| author_facet | Aisha Hill Madelon Morford Sharon Saydah Pamela Logan Danielle Raso Erin C. Stone Joanna Taliano Emilia H. Koumans Olga Varechtchouk |
| author_sort | Aisha Hill |
| collection | DOAJ |
| description | Introduction:
While various demographic factors and underlying medical conditions are associated with the development of post-COVID conditions within a month after SARS-CoV-2 infection, less is known about factors associated with post-COVID symptoms that persist for 6 months or more. The aim of this review was to determine the association between underlying conditions, other risk factors, health behaviors, and the presence of symptoms ≥6 months after COVID-19.
Methods:
Studies reporting on post-COVID symptoms were searched in databases, including Medline, EMBASE, Global Health, PsycInfo, Scopus, CINAHL, Proquest, and WHO COVID-19 literature, from the beginning of the pandemic until November 2022. Studies were included if they reported on symptoms ≥6 months after COVID-19 and a relevant measure of association (adjusted or unadjusted odds or risk ratio).
Results:
A total of 17 studies with 109,293 participants met the inclusion criteria; they were conducted in China (3), Italy (3), Spain (3), Russia (2), France (1), Germany (1), Sweden (1), Scotland (1), United Kingdom (1), and the United States (1). When compared to males, female participants were at an increased risk of post-COVID-19 symptoms (risk ratio (RR): 1.24; adjusted odds ratio (aOR): 3.08). Underlying conditions, including COPD/lung disease, overweight status or obesity, hypertension, cardiovascular disease, and asthma, were identified as possibly being associated with an increased risk of post-COVID symptoms.
Conclusion:
Female gender and certain underlying medical conditions were associated with an increased risk of post-COVID symptoms ≥6 months after COVID-19. Further research is needed to better understand some of these associations and identify groups that are at increased risk for persistent post-COVID conditions. |
| format | Article |
| id | doaj-art-088cdc70de8145a58d43567565440c45 |
| institution | Kabale University |
| issn | 2249-4863 2278-7135 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj-art-088cdc70de8145a58d43567565440c452025-01-11T10:12:46ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632278-71352024-12-0113125868588410.4103/jfmpc.jfmpc_247_24The association between underlying conditions, risk factors, risk markers, and post-COVID conditions ≥6 months after COVID-19: A systematic reviewAisha HillMadelon MorfordSharon SaydahPamela LoganDanielle RasoErin C. StoneJoanna TalianoEmilia H. KoumansOlga VarechtchoukIntroduction: While various demographic factors and underlying medical conditions are associated with the development of post-COVID conditions within a month after SARS-CoV-2 infection, less is known about factors associated with post-COVID symptoms that persist for 6 months or more. The aim of this review was to determine the association between underlying conditions, other risk factors, health behaviors, and the presence of symptoms ≥6 months after COVID-19. Methods: Studies reporting on post-COVID symptoms were searched in databases, including Medline, EMBASE, Global Health, PsycInfo, Scopus, CINAHL, Proquest, and WHO COVID-19 literature, from the beginning of the pandemic until November 2022. Studies were included if they reported on symptoms ≥6 months after COVID-19 and a relevant measure of association (adjusted or unadjusted odds or risk ratio). Results: A total of 17 studies with 109,293 participants met the inclusion criteria; they were conducted in China (3), Italy (3), Spain (3), Russia (2), France (1), Germany (1), Sweden (1), Scotland (1), United Kingdom (1), and the United States (1). When compared to males, female participants were at an increased risk of post-COVID-19 symptoms (risk ratio (RR): 1.24; adjusted odds ratio (aOR): 3.08). Underlying conditions, including COPD/lung disease, overweight status or obesity, hypertension, cardiovascular disease, and asthma, were identified as possibly being associated with an increased risk of post-COVID symptoms. Conclusion: Female gender and certain underlying medical conditions were associated with an increased risk of post-COVID symptoms ≥6 months after COVID-19. Further research is needed to better understand some of these associations and identify groups that are at increased risk for persistent post-COVID conditions.https://journals.lww.com/10.4103/jfmpc.jfmpc_247_24covid-19genderpost-covid conditionspost-covid symptomsunderlying conditions |
| spellingShingle | Aisha Hill Madelon Morford Sharon Saydah Pamela Logan Danielle Raso Erin C. Stone Joanna Taliano Emilia H. Koumans Olga Varechtchouk The association between underlying conditions, risk factors, risk markers, and post-COVID conditions ≥6 months after COVID-19: A systematic review Journal of Family Medicine and Primary Care covid-19 gender post-covid conditions post-covid symptoms underlying conditions |
| title | The association between underlying conditions, risk factors, risk markers, and post-COVID conditions ≥6 months after COVID-19: A systematic review |
| title_full | The association between underlying conditions, risk factors, risk markers, and post-COVID conditions ≥6 months after COVID-19: A systematic review |
| title_fullStr | The association between underlying conditions, risk factors, risk markers, and post-COVID conditions ≥6 months after COVID-19: A systematic review |
| title_full_unstemmed | The association between underlying conditions, risk factors, risk markers, and post-COVID conditions ≥6 months after COVID-19: A systematic review |
| title_short | The association between underlying conditions, risk factors, risk markers, and post-COVID conditions ≥6 months after COVID-19: A systematic review |
| title_sort | association between underlying conditions risk factors risk markers and post covid conditions ≥6 months after covid 19 a systematic review |
| topic | covid-19 gender post-covid conditions post-covid symptoms underlying conditions |
| url | https://journals.lww.com/10.4103/jfmpc.jfmpc_247_24 |
| work_keys_str_mv | AT aishahill theassociationbetweenunderlyingconditionsriskfactorsriskmarkersandpostcovidconditions6monthsaftercovid19asystematicreview AT madelonmorford theassociationbetweenunderlyingconditionsriskfactorsriskmarkersandpostcovidconditions6monthsaftercovid19asystematicreview AT sharonsaydah theassociationbetweenunderlyingconditionsriskfactorsriskmarkersandpostcovidconditions6monthsaftercovid19asystematicreview AT pamelalogan theassociationbetweenunderlyingconditionsriskfactorsriskmarkersandpostcovidconditions6monthsaftercovid19asystematicreview AT danielleraso theassociationbetweenunderlyingconditionsriskfactorsriskmarkersandpostcovidconditions6monthsaftercovid19asystematicreview AT erincstone theassociationbetweenunderlyingconditionsriskfactorsriskmarkersandpostcovidconditions6monthsaftercovid19asystematicreview AT joannataliano theassociationbetweenunderlyingconditionsriskfactorsriskmarkersandpostcovidconditions6monthsaftercovid19asystematicreview AT emiliahkoumans theassociationbetweenunderlyingconditionsriskfactorsriskmarkersandpostcovidconditions6monthsaftercovid19asystematicreview AT olgavarechtchouk theassociationbetweenunderlyingconditionsriskfactorsriskmarkersandpostcovidconditions6monthsaftercovid19asystematicreview AT aishahill associationbetweenunderlyingconditionsriskfactorsriskmarkersandpostcovidconditions6monthsaftercovid19asystematicreview AT madelonmorford associationbetweenunderlyingconditionsriskfactorsriskmarkersandpostcovidconditions6monthsaftercovid19asystematicreview AT sharonsaydah associationbetweenunderlyingconditionsriskfactorsriskmarkersandpostcovidconditions6monthsaftercovid19asystematicreview AT pamelalogan associationbetweenunderlyingconditionsriskfactorsriskmarkersandpostcovidconditions6monthsaftercovid19asystematicreview AT danielleraso associationbetweenunderlyingconditionsriskfactorsriskmarkersandpostcovidconditions6monthsaftercovid19asystematicreview AT erincstone associationbetweenunderlyingconditionsriskfactorsriskmarkersandpostcovidconditions6monthsaftercovid19asystematicreview AT joannataliano associationbetweenunderlyingconditionsriskfactorsriskmarkersandpostcovidconditions6monthsaftercovid19asystematicreview AT emiliahkoumans associationbetweenunderlyingconditionsriskfactorsriskmarkersandpostcovidconditions6monthsaftercovid19asystematicreview AT olgavarechtchouk associationbetweenunderlyingconditionsriskfactorsriskmarkersandpostcovidconditions6monthsaftercovid19asystematicreview |