Enhancing zein functionality through sequential limited Alcalase hydrolysis and transglutaminase treatment: Structural changes and functional properties

This study investigated the effects of sequential enzymatic hydrolysis using Alcalase, followed by transglutaminase conjugation on the secondary and tertiary structures, hydrophobicity, free amine content, protein-protein interactions, and functional properties of zein. Fourier-transform infrared sp...

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Main Authors: Adieh Anvar, Mohammad Hossein Azizi, Hassan Ahmadi Gavlighi
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Food Chemistry: X
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590157524008459
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author Adieh Anvar
Mohammad Hossein Azizi
Hassan Ahmadi Gavlighi
author_facet Adieh Anvar
Mohammad Hossein Azizi
Hassan Ahmadi Gavlighi
author_sort Adieh Anvar
collection DOAJ
description This study investigated the effects of sequential enzymatic hydrolysis using Alcalase, followed by transglutaminase conjugation on the secondary and tertiary structures, hydrophobicity, free amine content, protein-protein interactions, and functional properties of zein. Fourier-transform infrared spectroscopy showed that the most significant secondary structural changes, characterized by a decrease in α-helix content and an increase in β-turns, occurred at a higher degree of hydrolysis. At a 2 % degree of hydrolysis, it revealed notable emulsifying activity (65.96 m2/g), while at 5 % hydrolysis, it achieved the highest solubility (75.06 %). Additionally, the zein hydrolysate with a 7 % hydrolysis degree, treated with transglutaminase, demonstrated improved H0 values (2992.33), enhanced foam capacity (65.95 %), and increased solubilized protein content in a dithiothreitol extractant (31.35 %). Meanwhile, native zein treated with transglutaminase showed the highest water holding capacity (4.47 g/g). Overall, the combined enzymatic approach modified zein structure and properties, suggesting potential for improving functionality in plant-based food applications.
format Article
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institution Kabale University
issn 2590-1575
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publishDate 2024-12-01
publisher Elsevier
record_format Article
series Food Chemistry: X
spelling doaj-art-0834db1ee88d4ce8b86698db61161ceb2024-12-13T11:01:59ZengElsevierFood Chemistry: X2590-15752024-12-0124101957Enhancing zein functionality through sequential limited Alcalase hydrolysis and transglutaminase treatment: Structural changes and functional propertiesAdieh Anvar0Mohammad Hossein Azizi1Hassan Ahmadi Gavlighi2Department of Food Science and Technology, Faculty of Agriculture, Tarbiat Modares University, Tehran, Iran; Halal Research Center of IRI, Iran Food and Drug Administration, Ministry of Health and Medical Education, Tehran, IranCorresponding authors.; Department of Food Science and Technology, Faculty of Agriculture, Tarbiat Modares University, Tehran, Iran; Halal Research Center of IRI, Iran Food and Drug Administration, Ministry of Health and Medical Education, Tehran, IranCorresponding authors.; Department of Food Science and Technology, Faculty of Agriculture, Tarbiat Modares University, Tehran, Iran; Halal Research Center of IRI, Iran Food and Drug Administration, Ministry of Health and Medical Education, Tehran, IranThis study investigated the effects of sequential enzymatic hydrolysis using Alcalase, followed by transglutaminase conjugation on the secondary and tertiary structures, hydrophobicity, free amine content, protein-protein interactions, and functional properties of zein. Fourier-transform infrared spectroscopy showed that the most significant secondary structural changes, characterized by a decrease in α-helix content and an increase in β-turns, occurred at a higher degree of hydrolysis. At a 2 % degree of hydrolysis, it revealed notable emulsifying activity (65.96 m2/g), while at 5 % hydrolysis, it achieved the highest solubility (75.06 %). Additionally, the zein hydrolysate with a 7 % hydrolysis degree, treated with transglutaminase, demonstrated improved H0 values (2992.33), enhanced foam capacity (65.95 %), and increased solubilized protein content in a dithiothreitol extractant (31.35 %). Meanwhile, native zein treated with transglutaminase showed the highest water holding capacity (4.47 g/g). Overall, the combined enzymatic approach modified zein structure and properties, suggesting potential for improving functionality in plant-based food applications.http://www.sciencedirect.com/science/article/pii/S2590157524008459Foam capacityHydrolysisSolubilityTransglutaminaseZein
spellingShingle Adieh Anvar
Mohammad Hossein Azizi
Hassan Ahmadi Gavlighi
Enhancing zein functionality through sequential limited Alcalase hydrolysis and transglutaminase treatment: Structural changes and functional properties
Food Chemistry: X
Foam capacity
Hydrolysis
Solubility
Transglutaminase
Zein
title Enhancing zein functionality through sequential limited Alcalase hydrolysis and transglutaminase treatment: Structural changes and functional properties
title_full Enhancing zein functionality through sequential limited Alcalase hydrolysis and transglutaminase treatment: Structural changes and functional properties
title_fullStr Enhancing zein functionality through sequential limited Alcalase hydrolysis and transglutaminase treatment: Structural changes and functional properties
title_full_unstemmed Enhancing zein functionality through sequential limited Alcalase hydrolysis and transglutaminase treatment: Structural changes and functional properties
title_short Enhancing zein functionality through sequential limited Alcalase hydrolysis and transglutaminase treatment: Structural changes and functional properties
title_sort enhancing zein functionality through sequential limited alcalase hydrolysis and transglutaminase treatment structural changes and functional properties
topic Foam capacity
Hydrolysis
Solubility
Transglutaminase
Zein
url http://www.sciencedirect.com/science/article/pii/S2590157524008459
work_keys_str_mv AT adiehanvar enhancingzeinfunctionalitythroughsequentiallimitedalcalasehydrolysisandtransglutaminasetreatmentstructuralchangesandfunctionalproperties
AT mohammadhosseinazizi enhancingzeinfunctionalitythroughsequentiallimitedalcalasehydrolysisandtransglutaminasetreatmentstructuralchangesandfunctionalproperties
AT hassanahmadigavlighi enhancingzeinfunctionalitythroughsequentiallimitedalcalasehydrolysisandtransglutaminasetreatmentstructuralchangesandfunctionalproperties