Identifying multimorbidity patterns of non-communicable diseases in paediatric inpatients: a cross-sectional study in Shanghai, China

Objectives To enhance the understanding of non-communicable disease (NCD) multimorbidity in children who are inpatients by delineating the characteristics of and identifying patterns among paediatric inpatients with multimorbidity in China.Design Cross-sectional study.Setting Paediatric wards (n=17)...

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Main Authors: Chen Chen, Wenya Yu, Qian Liu, Yan Yang, Liang Zhou, Jianwei Shi, Hua Jin, Zhaoxin Wang, Jiaoling Huang, Ning Chen, Xiaoxiao Shi, Zhaohu Yu
Format: Article
Language:English
Published: BMJ Publishing Group 2021-04-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/11/4/e042679.full
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author Chen Chen
Wenya Yu
Qian Liu
Yan Yang
Liang Zhou
Jianwei Shi
Hua Jin
Zhaoxin Wang
Jiaoling Huang
Ning Chen
Xiaoxiao Shi
Zhaohu Yu
author_facet Chen Chen
Wenya Yu
Qian Liu
Yan Yang
Liang Zhou
Jianwei Shi
Hua Jin
Zhaoxin Wang
Jiaoling Huang
Ning Chen
Xiaoxiao Shi
Zhaohu Yu
author_sort Chen Chen
collection DOAJ
description Objectives To enhance the understanding of non-communicable disease (NCD) multimorbidity in children who are inpatients by delineating the characteristics of and identifying patterns among paediatric inpatients with multimorbidity in China.Design Cross-sectional study.Setting Paediatric wards (n=17) in Pudong New Area, Shanghai, China.Participants A total of 193 432 paediatric inpatients in the electronic health record systems of 17 hospitals from 2011 to 2016 participated in the study, and 91 004 children with NCDs were extracted and classified based on International Classification of Diseases, 10th version codes.Main outcome measures Number of the NCDs and multimorbidity patterns of the paediatric inpatients.Results In total, 47.05% (95% CI 46.83 to 47.27) of the paediatric inpatients had one or more chronic diseases, and 16.30% (95% CI 16.14 to 16.46) had multimorbidity. Congenital anomalies accounted for 19.43% (95% CI 19.25 to 19.61) of the principal diagnoses among the paediatric inpatients. Five common multimorbidity patterns were identified: a neurological-respiratory cluster, a neurological-respiratory-ear cluster, a cardiovascular-circulatory cluster, a genitourinary cluster (boy group) and a musculoskeletal-connective cluster (10–18 years age group).Conclusions Multimorbidity in paediatric inpatients suggests that decisions about reasonable allocation of paediatric inpatient resources should be fully considered. Multimorbidity patterns in paediatric inpatients revealed that prevention, including innovative treatments targeting children, should be further studied.
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spelling doaj-art-080a2112134d45e2bb963c92cf4dee3f2024-11-21T19:30:08ZengBMJ Publishing GroupBMJ Open2044-60552021-04-0111410.1136/bmjopen-2020-042679Identifying multimorbidity patterns of non-communicable diseases in paediatric inpatients: a cross-sectional study in Shanghai, ChinaChen Chen0Wenya Yu1Qian Liu2Yan Yang3Liang Zhou4Jianwei Shi5Hua Jin6Zhaoxin Wang7Jiaoling Huang8Ning Chen9Xiaoxiao Shi10Zhaohu Yu116 Institute of Precision Medicine, Sun Yat-sen University First Affiliated Hospital, Guangzhou, Guangdong, ChinaSchool of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China3 Faculty of Psychology, Naval Medical University, Shanghai, People`s Republic of ChinaTongji University School of Economics and Management, Shanghai, China1 Department of Social Psychiatry, Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, Guangdong, ChinaSchool of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaGansu University of Chinese Medicine, Lanzhou, Gansu, ChinaSchool of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaShanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, ChinaDepartment of Epidemiology and Biostatistics, School of Public Health, Guangxi Medical University, Nanning, Guangxi, ChinaDepartment of General Practice, Tongji University Affiliated Yangpu Hospital, Shanghai, ChinaDepartment of Neurosurgery, Navy 971 Hospital, Qingdao, ChinaObjectives To enhance the understanding of non-communicable disease (NCD) multimorbidity in children who are inpatients by delineating the characteristics of and identifying patterns among paediatric inpatients with multimorbidity in China.Design Cross-sectional study.Setting Paediatric wards (n=17) in Pudong New Area, Shanghai, China.Participants A total of 193 432 paediatric inpatients in the electronic health record systems of 17 hospitals from 2011 to 2016 participated in the study, and 91 004 children with NCDs were extracted and classified based on International Classification of Diseases, 10th version codes.Main outcome measures Number of the NCDs and multimorbidity patterns of the paediatric inpatients.Results In total, 47.05% (95% CI 46.83 to 47.27) of the paediatric inpatients had one or more chronic diseases, and 16.30% (95% CI 16.14 to 16.46) had multimorbidity. Congenital anomalies accounted for 19.43% (95% CI 19.25 to 19.61) of the principal diagnoses among the paediatric inpatients. Five common multimorbidity patterns were identified: a neurological-respiratory cluster, a neurological-respiratory-ear cluster, a cardiovascular-circulatory cluster, a genitourinary cluster (boy group) and a musculoskeletal-connective cluster (10–18 years age group).Conclusions Multimorbidity in paediatric inpatients suggests that decisions about reasonable allocation of paediatric inpatient resources should be fully considered. Multimorbidity patterns in paediatric inpatients revealed that prevention, including innovative treatments targeting children, should be further studied.https://bmjopen.bmj.com/content/11/4/e042679.full
spellingShingle Chen Chen
Wenya Yu
Qian Liu
Yan Yang
Liang Zhou
Jianwei Shi
Hua Jin
Zhaoxin Wang
Jiaoling Huang
Ning Chen
Xiaoxiao Shi
Zhaohu Yu
Identifying multimorbidity patterns of non-communicable diseases in paediatric inpatients: a cross-sectional study in Shanghai, China
BMJ Open
title Identifying multimorbidity patterns of non-communicable diseases in paediatric inpatients: a cross-sectional study in Shanghai, China
title_full Identifying multimorbidity patterns of non-communicable diseases in paediatric inpatients: a cross-sectional study in Shanghai, China
title_fullStr Identifying multimorbidity patterns of non-communicable diseases in paediatric inpatients: a cross-sectional study in Shanghai, China
title_full_unstemmed Identifying multimorbidity patterns of non-communicable diseases in paediatric inpatients: a cross-sectional study in Shanghai, China
title_short Identifying multimorbidity patterns of non-communicable diseases in paediatric inpatients: a cross-sectional study in Shanghai, China
title_sort identifying multimorbidity patterns of non communicable diseases in paediatric inpatients a cross sectional study in shanghai china
url https://bmjopen.bmj.com/content/11/4/e042679.full
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