Role of Rab13, Protein Kinase A, and Zonula Occludens-1 in Hepatitis E Virus Entry and Cell-to-Cell Spread: Comparative Analysis of Quasi-Enveloped and Non-Enveloped Forms

Role of Rab13, Protein Kinase A, and Zonula Occludens-1 in Hepatitis E Virus Entry and Cell-to-Cell Spread: Comparative Analysis of Quasi-Enveloped and Non-Enveloped Forms

Hepatitis E virus (HEV) exists in two distinct forms: a non-enveloped form (neHEV), which is present in feces and bile, and a quasi-enveloped form (eHEV), found in circulating blood and culture supernatants. This study aimed to elucidate the roles of Ras-associated binding 13 (Rab13) and protein kin...

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Bibliographic Details
Main Authors: Shigeo Nagashima, Putu Prathiwi Primadharsini, Masaharu Takahashi, Takashi Nishiyama, Kazumoto Murata, Hiroaki Okamoto
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pathogens
Subjects:
hepatitis E virus
Rab13
protein kinase A
tight junction protein
zonula occludens-1
HEV entry
Online Access:https://www.mdpi.com/2076-0817/13/12/1130
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