Prevalence of Intensive-care-unit-acquired Thrombocytopenia in a Tertiary Care Hospital in Sudan

Thrombocytopenia is a common finding in patients admitted to the Intensive Care Unit (ICU). This can be attributed to the wide spectrum of comorbidities that affect homeostasis in these patients. The aim of this study was to estimate the frequency of thrombocytopenia among patients admitted to the m...

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Main Authors: Sara Rahama, Kamal Mirghani, Mustafa Hussein, Sami Menasri
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-06-01
Series:Dr. Sulaiman Al Habib Medical Journal
Subjects:
Online Access:https://journals.lww.com/10.2991/dsahmj.k.190617.002
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author Sara Rahama
Kamal Mirghani
Mustafa Hussein
Sami Menasri
author_facet Sara Rahama
Kamal Mirghani
Mustafa Hussein
Sami Menasri
author_sort Sara Rahama
collection DOAJ
description Thrombocytopenia is a common finding in patients admitted to the Intensive Care Unit (ICU). This can be attributed to the wide spectrum of comorbidities that affect homeostasis in these patients. The aim of this study was to estimate the frequency of thrombocytopenia among patients admitted to the medical ICU of Omdurman Military Hospital, Sudan. An observational descriptive hospital-based cross-sectional survey was conducted to calculate the prevalence of ICU-acquired thrombocytopenia among patients admitted to the medical ICU of Omdurman Military Hospital. Patients were excluded if they had a platelet count <150,000/mm3 upon admission or if their platelet count dropped below that level <5 days post-admission. Among 160 patients, 112 (70%) developed thrombocytopenia. The mean platelet count upon admission was 237,600 ± 4,600/mm3. The use of thromboprophylaxis, antibiotics, sedation, and mechanical ventilatory support was significantly correlated with the drop in platelet count (p < 0.05). The study is probably the first of its kind to draw attention to the magnitude of ICU-acquired thrombocytopenia in Sudan. The results showed a significant impact of the blood disorder in the critical care setting. Several factors have been associated with the abnormality. The development of thrombocytopenia can carry unfavourable outcomes in terms of morbidity and mortality. Therefore, the detection of this abnormal parameter needs a prompt response.
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record_format Article
series Dr. Sulaiman Al Habib Medical Journal
spelling doaj-art-0761e3838bcf4a12a3607cf235fd34f82025-08-20T04:01:25ZengWolters Kluwer Medknow PublicationsDr. Sulaiman Al Habib Medical Journal2666-819X2590-33492019-06-0111-2121510.2991/dsahmj.k.190617.002Prevalence of Intensive-care-unit-acquired Thrombocytopenia in a Tertiary Care Hospital in SudanSara RahamaKamal MirghaniMustafa HusseinSami MenasriThrombocytopenia is a common finding in patients admitted to the Intensive Care Unit (ICU). This can be attributed to the wide spectrum of comorbidities that affect homeostasis in these patients. The aim of this study was to estimate the frequency of thrombocytopenia among patients admitted to the medical ICU of Omdurman Military Hospital, Sudan. An observational descriptive hospital-based cross-sectional survey was conducted to calculate the prevalence of ICU-acquired thrombocytopenia among patients admitted to the medical ICU of Omdurman Military Hospital. Patients were excluded if they had a platelet count <150,000/mm3 upon admission or if their platelet count dropped below that level <5 days post-admission. Among 160 patients, 112 (70%) developed thrombocytopenia. The mean platelet count upon admission was 237,600 ± 4,600/mm3. The use of thromboprophylaxis, antibiotics, sedation, and mechanical ventilatory support was significantly correlated with the drop in platelet count (p < 0.05). The study is probably the first of its kind to draw attention to the magnitude of ICU-acquired thrombocytopenia in Sudan. The results showed a significant impact of the blood disorder in the critical care setting. Several factors have been associated with the abnormality. The development of thrombocytopenia can carry unfavourable outcomes in terms of morbidity and mortality. Therefore, the detection of this abnormal parameter needs a prompt response.https://journals.lww.com/10.2991/dsahmj.k.190617.002critical careintensive care unitplatelet countthrombocytopenia
spellingShingle Sara Rahama
Kamal Mirghani
Mustafa Hussein
Sami Menasri
Prevalence of Intensive-care-unit-acquired Thrombocytopenia in a Tertiary Care Hospital in Sudan
Dr. Sulaiman Al Habib Medical Journal
critical care
intensive care unit
platelet count
thrombocytopenia
title Prevalence of Intensive-care-unit-acquired Thrombocytopenia in a Tertiary Care Hospital in Sudan
title_full Prevalence of Intensive-care-unit-acquired Thrombocytopenia in a Tertiary Care Hospital in Sudan
title_fullStr Prevalence of Intensive-care-unit-acquired Thrombocytopenia in a Tertiary Care Hospital in Sudan
title_full_unstemmed Prevalence of Intensive-care-unit-acquired Thrombocytopenia in a Tertiary Care Hospital in Sudan
title_short Prevalence of Intensive-care-unit-acquired Thrombocytopenia in a Tertiary Care Hospital in Sudan
title_sort prevalence of intensive care unit acquired thrombocytopenia in a tertiary care hospital in sudan
topic critical care
intensive care unit
platelet count
thrombocytopenia
url https://journals.lww.com/10.2991/dsahmj.k.190617.002
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AT kamalmirghani prevalenceofintensivecareunitacquiredthrombocytopeniainatertiarycarehospitalinsudan
AT mustafahussein prevalenceofintensivecareunitacquiredthrombocytopeniainatertiarycarehospitalinsudan
AT samimenasri prevalenceofintensivecareunitacquiredthrombocytopeniainatertiarycarehospitalinsudan